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  • Penyakit Langka Sindrom Stevens Johnson, Begini Gejalanya

Penyakit Langka Sindrom Stevens Johnson, Begini Gejalanya

Penyakit Langka Sindrom Stevens Johnson, Begini Gejalanya
Credits: Freepik

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Stevens-Johnson Syndrome (SJS) is a rare, serious disorder of the skin and mucous membranes in the body such as the eyes, genitals and mouth. The exact cause of this condition is not always known. However, SJS is usually triggered by medication, infection, or both.

Some drugs, such as anti-gout drugs, drugs to treat seizures, sulfonamide antibiotics, and pain relievers, can trigger Stevens-Johnson syndrome. Apart from that, infections such as pneumonia and HIV infection are also said to be causes.

 

Symptoms of Stevens-Johnson Syndrome​

Stevens-Johnson syndrome often occurs in children and adults under 30 years of age. However, SJS can also be experienced by older or elderly people.

Early symptoms of Stevens-Johnson syndrome may begin with flu-like symptoms. Early symptoms that appear a few days before the rash include:

  • Fever
  • Pain or irritation in the mouth and throat
  • Unexplained feeling of tiredness
  • Burning sensation or irritation in the eyes

As the condition progresses, other signs and symptoms also develop, including:

  • Widespread skin pain
  • A red or purple rash appears that spreads to various parts of the body
  • The appearance of blisters on the skin and mucous membranes in the mouth, nose, eyes and genitals
  • The skin begins to peel

Read more: Why Do Women Tend To Experience Autoimmune Disease?

 

Is Stevens-Johnson Syndrome Deadly?

Stevens-Johnson syndrome has the potential to be a fatal condition, although the fatality rate depends on how severe the condition is and the response to treatment.

There are several complications associated with Stevens-Johnson syndrome that may occur, including:

  • Widespread pneumonia
  • Visual impairment and blindness
  • Permanent damage to the skin
  • Sepsis or severe infection in the bloodstream
  • Shock or circulatory failure as an inflammatory response to extensive tissue damage
  • Organ failure
  • Death

Read more: List Of Diseases Caused By Autoimmune Conditions

 

How to Prevent Stevens-Johnson Syndrome

Although there is no definite way to prevent Stevens-Johnson syndrome, you can still take several important steps, especially those related to the use of certain medications and infections, including:

  • Communicate with your doctor about any history of allergies or drug reactions you have experienced before
  • Note and avoid drugs that have the potential to cause allergic reactions
  • Pay attention to unusual symptoms or suspicious reactions after taking medication such as rash, swelling, or unusual pain
  • Don't take medicine carelessly and always consult a doctor before taking medicine
  • Consult a doctor if you have concerns about the medication you are using

 

These steps do not guarantee the prevention of Steven Johnson syndrome, but we hope they will help to reduce the risks and adverse reactions that can be experienced. You can also consult with our doctors regarding medication consumption and concerns about allergic reactions through the Ai Care application, which can be downloaded from the App Store or Play Store.

 

Want to know more information about other diseases? Click here!

 

 

Writer : Agatha Writer
Editor :
  • dr. Monica Salim
Last Updated : Rabu, 6 Maret 2024 | 09:37

Mayo Clinic (2023). Stevens-Johnson syndrome. Available from: https://www.mayoclinic.org/diseases-conditions/stevens-johnson-syndrome/symptoms-causes/syc-20355936 

Amanda M. Oakley and Karthik Krishnamurthy (2023). Stevens-Johnson Syndrome. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459323/ 

Cleveland Clinic (2020). Stevens-Johnson Syndrome. Available from: https://my.clevelandclinic.org/health/diseases/17656-stevens-johnson-syndrome 

Esen Karamursel Akpek, MD. Stevens-Johnson Syndrome. Available from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/stevens-johnson-syndrome 

Natasha Camargo da Silva, et all (2020). Stevens Johnson Syndrome in Patients with HIV: A Challenging Treatment. Available from: https://www.oooojournal.net/article/S2212-4403(20)30384-9/abstract 

Drugs.com (2024). Stevens-Johnson Syndrome. Available from: https://www.drugs.com/cg/stevens-johnson-syndrome.html 

Mayo Clinic (2022). Drug allergy. Available from: https://www.mayoclinic.org/diseases-conditions/drug-allergy/symptoms-causes/syc-20371835 

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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new5.11msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9176 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9176
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
      • 0: 3150
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new4.86msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8168 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8168
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
      • 0: 9653
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new5.21msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8073 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8073
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
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      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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    App\Models\Admin\Category
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    App\Models\Admin\Tag
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