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Mengenal Diabetes Tipe 3 dan Hubungannya dengan Alzheimer

Mengenal Diabetes Tipe 3 dan Hubungannya dengan Alzheimer
Ilustrasi diabetes. Credit: Freepik

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Selama ini Anda mungkin lebih mengenal diabetes tipe 1, tipe 2 dan diabetes gestasional. Namun ada juga kondisi medis diabetes tipe 3 yang berkaitan dengan Alzheimer. Apa perbedaan diabetes tipe 3 dengan tipe diabetes lainnya dan apa hubungannya dengan Alzheimer? Simak ulasannya berikut ini.

 

Apa Itu Diabetes Tipe 3?

Diabetes tipe 3 sebenarnya bukan istilah yang diakui secara medis maupun istilah yang digunakan untuk melakukan diagnosis pada penyakit. Peneliti menggunakan istilah diabetes tipe 3 untuk mengungkapkan hipotesis bahwa penyakit Alzheimer disebabkan oleh resistensi insulin dan disfungsi faktor pertumbuhan hormon mirip insulin yang terjadi secara spesifik di otak.

Diabetes tipe 3 juga digunakan para peneliti untuk menggambarkan diabetes tipe 2 dan didiagnosis mengalami Alzheimer. Namun klasifikasi diabetes tipe 3 dianggap kontroversial dan tidak diterima oleh organisasi kesehatan dan American Diabetes Association.

Selain diabetes tipe 3, ada pula kondisi diabetes tipe 3c yang berkaitan dengan kerusakan organ pankreas. Diabetes ini berkembang akibat adanya kerusakan pada organ di pankreas. Meskipun memiliki nama yang mirip, namun diabetes tipe 3c adalah kondisi yang berbeda.

Baca Juga: Penyebab dan Faktor Risiko Diabetes Gestasional (Diabetes Selama Kehamilan)

 

Hubungan Antara Alzheimer dan Diabetes

Banyak anggapan bahwa jaringan otak tidak berkaitan dengan insulin. Namun sejumlah penelitian mengungkapkan bahwa respon otak terhadap insulin ternyata memengaruhi proses metabolisme otak dan bagaimana otak memberi sinyal kepada anggota tubuh untuk menjalankan fungsinya.

Dilansir dari Healthline, peneliti mengungkapkan bahwa diabetes dan Alzheimer saling berkaitan. Beberapa peneliti mengungkapkan bahwa penyakit Alzheimer dapat dipicu oleh resistensi insulin yang terjadi di otak.

Kondisi diabetes, terutama yang tidak dikontrol dengan baik dapat menyebabkan ketidakseimbangan senyawa di otak yang berkontribusi pada Alzheimer. Tingginya kadar gula darah juga memicu peradangan yang dapat merusak sel otak sehingga memicu diabetes.

Demensia vaskular adalah diagnosis yang berdiri sendiri dengan gejalanya sendiri, namun kondisi ini juga dapat menjadi tanda peringatan mengenai perkembangan penyakit Alzheimer. Hingga saat ini para peneliti masih melakukan penelitian untuk mengetahui hubungan antara penyakit Alzheimer, penyebabnya dan hubungannya dengan diabetes.

Baca Juga: Diabetes Hingga Stroke, Ini Masalah Kesehatan yang Berkaitan dengan Obesitas

 

Gejala Diabetes Tipe 3

Dilansir dari Medical News Today, karena istilah diabetes tipe 3 bukanlah istilah diagnostik, maka gejala diabetes tipe 3 tidak diklasifikasikan secara medis. Beberapa gejala diabetes tipe 3 dapat mencakup gejala awal penyakit Alzheimer di antaranya:

  • Kehilangan ingatan yang berdampak negatif pada kehidupan sehari-hari
  • Kesulitan menyelesaikan masalah atau membuat rencana
  • Kesulitan melaksanakan tugas-tugas harian
  • Kebingungan tentang lokasi atau waktu
  • Kesulitan menggunakan dan memahami bahasa tertulis dan lisan
  • Salah meletakkan sesuatu
  • Menarik diri dari aktivitas sosial atau pekerjaan
  • Perubahan suasana hati dan kepribadian

Beberapa gejala mirip dengan tanda-tanda penuaan sehingga gejala ini sering kali tidak disadari. Jika Anda mencurigai perubahan di atas pada kelompok lansia sebagai gejala Alzheimer maka sebaiknya periksakan ke dokter.

 

Hingga saat ini belum ada pengobatan untuk diabetes 3 atau penyakit Alzheimer. Penanganan yang diberikan dokter bertujuan untuk memperlambat perkembangan gejala yang muncul. Beberapa penanganan yang dapat diberikan antara lain pemberian obat-obatan untuk mencegah penurunan kemampuan kognitif.

Istilah diabetes tipe 3 bukanlah istilah medis dan istilah untuk diagnosis. Jika Anda memiliki pertanyaan seputar kesehatan, Anda bisa memanfaatkan fitur konsultasi pada aplikasi Ai Care.

 

Mau tahu informasi seputar penyakit lainnya? Cek di sini, ya!

Writer : Ratih AI Care
Editor :
  • dr Nadia Opmalina
Last Updated : Kamis, 30 Mei 2024 | 09:35

Hobbs, H. (2023). Type 3 Diabetes and Alzheimer’s Disease: What You Need to Know. Available from: https://www.healthline.com/health/type-3-diabetes

Richards, L. (2023). Type 3 diabetes explained. Available from: https://www.medicalnewstoday.com/articles/type-3-diabetes

Heerema, E. (2022). What Is Type 3 Diabetes?. Available from: https://www.verywellhealth.com/why-is-alzheimers-called-type-3-diabetes-98797

Salomon, S. (2021). Why Some Researchers Are Calling Alzheimer’s Disease a ‘Type 3 Diabetes’. Available from: https://www.everydayhealth.com/diabetes/alzheimers-disease-actually-type-diabetes/

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      Backtrace
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      Backtrace
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      Backtrace
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