Tiga Kelainan Kromosom yang Menyebabkan Keguguran di Trimester Pertama

Tiga Kelainan Kromosom yang Menyebabkan Keguguran di Trimester Pertama
Credits: Freepik

Bagikan :


Keguguran adalah berhentinya kehamilan sebelum usia kehamilan 20 minggu. Keguguran lebih sering terjadi terutama di trimester pertama kehamilan.

Kelainan kromosom adalah penyebab paling umum keguguran di trimester pertama kehamilan. Hal ini merupakan faktor di luar kendali Anda dan bukan akibat tindakan tertentu. Kelainan kromosom ini bisa terjadi selama pembuahan atau perkembangan embrio awal.

 

Kelainan Kromosom yang Menyebabkan Keguguran

Sebagian besar kasus keguguran terjadi karena janin tidak berkembang dengan baik di dalam rahim. Hal ini disebabkan karena adanya masalah kromosom.

Ketika sel telur dan sperma bertemu, dua set kromosom akan bergabung bersama. Jika salah satu set kromosom memiliki lebih sedikit atau lebih banyak dari biasanya, maka dapat menyebabkan keguguran.

Blighted ovum (kehamilan tanpa embrio)

Kehamilan tanpa embrio dikenal dengan istilah blighted ovum. Kondisi ini terjadi ketika sel telur yang dibuahi menempel dan membentuk kantung kehamilan, namun karena memiliki masalah kromosom, maka embrio gagal untuk tumbuh dan berkembang.

Blighted ovum menyebabkan keguguran dini di trimester pertama kehamilan, yang ditandai dengan gejala kehamilan dan hasil tes kehamilan positif, namun kemudian diikuti dengan perdarahan ringan, perdarahan disertai dengan keluarnya jaringan yang menggumpal, serta kram ringan hingga sedang di pinggul dan perut.

 

Baca Juga: Blighted Ovum (Kehamilan Kosong): Ketahui Penyebab dan Gejalanya

 

Intrauterine fetal death (IUFD)

IUFD adalah istilah yang menggambarkan kematian janin pada atau setelah minggu ke-20. Dalam situasi ini, embrio terbentuk, tetapi berhenti berkembang sehingga embrio mati sebelum ada gejala keguguran.

 

Hamil anggur

Hamil anggur adalah komplikasi kehamilan yang jarang terjadi. Kehamilan ini melibatkan pertumbuhan sel yang tidak biasa yang disebut trofoblas. Sel-sel ini seharusnya yang memberi makan janin untuk tumbuh dan berkembang.

Ada dua jenis kehamilan anggur, yaitu hamil anggur lengkap dan hamil anggur parsial. Pada hamil anggur lengkap, jaringan plasenta membengkak dan membentuk kista berisi cairan. Tidak ada janin yang tumbuh pada kehamilan ini. Sedangkan pada hamil anggur parsial, plasenta memiliki jaringan teratur dan tidak teratur. Janin juga mungkin ada, namun tidak dapat bertahan hidup sehingga Anda mengalami keguguran.

 

Baca Juga: Ketahui Penyebab dan Tanda-Tanda Bila Hamil Anggur

 

Hamil anggur terjadi ketika sel telur yang dibuahi mengalami kelainan dalam pembagian kromosom sehingga menyebabkan perkembangan yang tidak normal. Pada hamil anggur lengkap, pembuahan terjadi dengan satu atau dua sperma yang membuahi sel telur namun sel telur kehilangan sebagian besar materi genetiknya, sehingga hanya ada salinan kromosom ayah. Pada hamil anggur parsial, jumlah kromosom ada 69 di mana seharusnya ada 46. Kromosom ayah dan ibu tetap ada sebagian, namun ketika dua sperma membuahi sel telur yang sama, maka dapat terjadi kombinasi yang tidak normal yang membuat janin tidak berkembang.

 

Keguguran lebih mungkin dialami mereka yang hamil di atas usia 35 tahun, pernah mengalami keguguran sebelumnya, memiliki riwayat penyakit kronis, memiliki masalah berat badan (baik underweight maupun overweight), atau yang memiliki riwayat kelainan genetik. Bila memiliki kesemua hal tersebut, ada baiknya untuk berkonsultasi dengan dokter untuk merencanakan kehamilan yang sehat. Anda juga bisa memanfaatkan layanan konsultasi kesehatan daring terkait perencanaan kehamilan dengan mengunduh aplikasi Ai Care melalui App Store atau Play Store.

Mau tahu informasi seputar kehamilan, menyusui, kesehatan wanita dan anak-anak? Cek di sini, ya!

 

 

Mayo Clinic (2023). Miscarriage. Available from: https://www.mayoclinic.org/diseases-conditions/pregnancy-loss-miscarriage/symptoms-causes/syc-20354298 

Cleveland Clinic (2022). Miscarriage. Available from: https://my.clevelandclinic.org/health/diseases/9688-miscarriage 

Khalid Chaudhry, et all (2023). Anembryonic Pregnancy. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499938 

Cleveland Clinic (2021). Blighted Ovum. Available from: https://my.clevelandclinic.org/health/diseases/21924-blighted-ovum 

Cerebral Palsy (2023). Intrauterine fetal demise. Available from: https://www.cerebralpalsyguide.com/birth-injury/intrauterine-fetal-demise 

 

Mayo Clinic (2022). Molar pregnancy. Available from: https://www.mayoclinic.org/diseases-conditions/molar-pregnancy/symptoms-causes/syc-20375175 

Request history8.1.29PHP Version739msRequest Duration5MBMemory UsageGET {category}/{slug}Route
  • warninglog[07:49:17] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • warninglog[07:49:17] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • Booting (242ms)time
  • Application (497ms)time
  • 1 x Application (67.27%)
    497ms
    1 x Booting (32.73%)
    242ms
    11 templates were rendered
    • 1x web.v2.single-post-healthpediasingle-post-healthpedia.blade.php#?blade
    • 1x web.v2.partials.single.breadcrumbbreadcrumb.blade.php#?blade
    • 2x web.partials.single-sharesingle-share.blade.php#?blade
    • 1x web.v2.partials.single.editoreditor.blade.php#?blade
    • 1x web.v2.partials.single.tagstags.blade.php#?blade
    • 1x web.v2.partials.single.referensireferensi.blade.php#?blade
    • 1x web.v2.partials.article-populararticle-popular.blade.php#?blade
    • 1x web.v2.partials.related-articlerelated-article.blade.php#?blade
    • 1x web.v2.partials.healthtopichealthtopic.blade.php#?blade
    • 1x layouts.v2.web_layoutweb_layout.blade.php#?blade
    uri
    GET {category}/{slug}
    middleware
    web
    controller
    App\Http\Controllers\WebController@newSinglePost
    namespace
    App\Http\Controllers
    prefix
    where
    as
    web.new.single.post
    file
    app/Http/Controllers/WebController.php:645-806
    32 statements were executed406ms
    • WebController.php#656aicare_prod_new850μsselect * from `categories` where (`slug` = 'ibu-dan-anak' or `slug_en` = 'ibu-dan-anak') and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: ibu-dan-anak
      • 1: ibu-dan-anak
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • app/Http/Controllers/WebController.php:656
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#657aicare_prod_new48.1msselect * from `posts` where (`slug` = 'tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama' or `slug_en` = 'tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama') and `posts`.`deleted_at` is null limit 1
      Bindings
      • 0: tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama
      • 1: tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • app/Http/Controllers/WebController.php:657
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#703aicare_prod_new36.9msselect * from `posts` where (`slug` = 'tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama' or `slug_en` = 'tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama') and `status` = 1 and `publish_date` <= '2025-04-08 07:49:17' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
      Bindings
      • 0: tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama
      • 1: tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama
      • 2: 1
      • 3: 2025-04-08 07:49:17
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • app/Http/Controllers/WebController.php:703
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#703aicare_prod_new1.05msselect `users`.*, `post_editor`.`post_id` as `pivot_post_id`, `post_editor`.`user_id` as `pivot_user_id`, `post_editor`.`created_at` as `pivot_created_at`, `post_editor`.`updated_at` as `pivot_updated_at` from `users` inner join `post_editor` on `users`.`id` = `post_editor`.`user_id` where `post_editor`.`post_id` in (8141)
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:703
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#703aicare_prod_new770μsselect `users`.*, `post_english_editors`.`post_id` as `pivot_post_id`, `post_english_editors`.`user_id` as `pivot_user_id`, `post_english_editors`.`created_at` as `pivot_created_at`, `post_english_editors`.`updated_at` as `pivot_updated_at` from `users` inner join `post_english_editors` on `users`.`id` = `post_english_editors`.`user_id` where `post_english_editors`.`post_id` in (8141)
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:703
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#703aicare_prod_new5.77msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` in (8141) and `categories`.`deleted_at` is null
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:703
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#703aicare_prod_new660μsselect * from `categories` where `categories`.`id` in (0) and `categories`.`deleted_at` is null
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:703
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#724aicare_prod_new15.18msselect `tags`.*, `post_tag`.`post_id` as `pivot_post_id`, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`created_at` as `pivot_created_at`, `post_tag`.`updated_at` as `pivot_updated_at` from `tags` inner join `post_tag` on `tags`.`id` = `post_tag`.`tag_id` where `post_tag`.`post_id` = 8141
      Bindings
      • 0: 8141
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:724
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#1360aicare_prod_new12.43msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 555 and `posts`.`deleted_at` is null
      Bindings
      • 0: 555
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:1360
      • app/Http/Controllers/WebController.php:735
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#1360aicare_prod_new13.53msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 900 and `posts`.`deleted_at` is null
      Bindings
      • 0: 900
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:1360
      • app/Http/Controllers/WebController.php:735
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#1360aicare_prod_new12.15msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 1274 and `posts`.`deleted_at` is null
      Bindings
      • 0: 1274
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:1360
      • app/Http/Controllers/WebController.php:735
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#1360aicare_prod_new12.25msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 5598 and `posts`.`deleted_at` is null
      Bindings
      • 0: 5598
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:1360
      • app/Http/Controllers/WebController.php:735
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#739aicare_prod_new123msselect * from `posts` where `status` = 1 and `publish_date` <= '2025-04-08 07:49:17' and `deleted_at` is null and `content_type` = 'article' and `posts`.`deleted_at` is null order by RAND() limit 7
      Bindings
      • 0: 1
      • 1: 2025-04-08 07:49:17
      • 2: article
      Hints
      • Use SELECT * only if you need all columns from table
      • ORDER BY RAND() is slow, try to avoid if you can. You can read this or this
      Backtrace
      • app/Http/Controllers/WebController.php:739
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • CategoryHealtTopics.php#11aicare_prod_new1.18msselect * from `categories` where (`slug` != 'penyakit-a-z' and `slug` != 'obat-a-z' and `slug` != 'pemeriksaan-a-z' and `parent_id` = '0') and `categories`.`deleted_at` is null order by `order` asc
      Bindings
      • 0: penyakit-a-z
      • 1: obat-a-z
      • 2: pemeriksaan-a-z
      • 3: 0
      Hints
      • Use SELECT * only if you need all columns from table
      • The != operator is not standard. Use the <> operator to test for inequality instead.
      Backtrace
      • app/Repositories/Categories/CategoryHealtTopics.php:11
      • app/Http/Controllers/WebController.php:740
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#748aicare_prod_new1.66msselect `healthpedia`.*, `healthpedia_post`.`post_id` as `pivot_post_id`, `healthpedia_post`.`healthpedia_id` as `pivot_healthpedia_id`, `healthpedia_post`.`created_at` as `pivot_created_at`, `healthpedia_post`.`updated_at` as `pivot_updated_at` from `healthpedia` inner join `healthpedia_post` on `healthpedia`.`id` = `healthpedia_post`.`healthpedia_id` where `healthpedia_post`.`post_id` = 8141 and `healthpedia`.`deleted_at` is null
      Bindings
      • 0: 8141
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • app/Http/Controllers/WebController.php:748
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#779aicare_prod_new11.33msupdate `posts` set `views_count` = 477 where `id` = 8141
      Bindings
      • 0: 477
      • 1: 8141
      Backtrace
      • app/Http/Controllers/WebController.php:779
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • ActivityLogger.php#174aicare_prod_new8.64msinsert into `activity_log` (`log_name`, `properties`, `batch_uuid`, `event`, `subject_id`, `subject_type`, `description`, `updated_at`, `created_at`) values ('default', '[]', null, 'updated', 8141, 'App\\Models\\Admin\\Post', 'updated', '2025-04-08 07:49:17', '2025-04-08 07:49:17')
      Bindings
      • 0: default
      • 1: []
      • 2: 
      • 3: updated
      • 4: 8141
      • 5: App\Models\Admin\Post
      • 6: updated
      • 7: 2025-04-08 07:49:17
      • 8: 2025-04-08 07:49:17
      Backtrace
      • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
      • vendor/spatie/laravel-activitylog/src/Traits/LogsActivity.php:88
      • app/Http/Controllers/WebController.php:779
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • single-post-healthpedia.blade.php#37aicare_prod_new1.22msselect * from `users` where `users`.`id` = 20 limit 1
      Bindings
      • 0: 20
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.single-post-healthpedia:37
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4093 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4093
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.68msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4154 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4154
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.64msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 2463 and `categories`.`deleted_at` is null
      Bindings
      • 0: 2463
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.52msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6677 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6677
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.61msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4892 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4892
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.47msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9872 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9872
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.67msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7884 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7884
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new8msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8864 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8864
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.92msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 1030 and `categories`.`deleted_at` is null
      Bindings
      • 0: 1030
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new11.24msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8224 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8224
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.09msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8209 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8209
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#122aicare_prod_new1.13msselect * from `pages` where `slug` = 'about-us' limit 1
      Bindings
      • 0: about-us
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:122
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#547aicare_prod_new890μsselect * from `faqs` limit 1
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#551aicare_prod_new1.09msselect * from `term_policies`
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
    70Post.php#?
    App\Models\Admin\Category
    19Category.php#?
    App\Models\Admin\Tag
    4Tag.php#?
    App\Models\TermPolicy
    3TermPolicy.php#?
    App\User
    1User.php#?
    App\Models\Admin\Page
    1Page.php#?
    App\Models\Admin\Faq
    1Faq.php#?
        locale
        id
        _token
        voqJApIAN4Fv7os2CCgc65qhRmMTZ4dR7lbIP2j8
        _previous
        array:1 [ "url" => "https://ai-care.atmatech.id/ibu-dan-anak/tiga-kelainan-kromosom-yang-menyebabk...
        _flash
        array:2 [ "old" => [] "new" => [] ]
        path_info
        /ibu-dan-anak/tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:19 [ "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "x-real-ip" => array:1 [ 0 => "18.218.140.12" ] "x-forwarded-for" => array:1 [ 0 => "18.218.140.12" ] "x-forwarded-proto" => array:1 [ 0 => "https" ] "x-forwarded-scheme" => array:1 [ 0 => "https" ] "host" => array:1 [ 0 => "ai-care.atmatech.id" ] "connection" => array:1 [ 0 => "keep-alive" ] ]
        request_cookies
        []
        
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Tue, 08 Apr 2025 00:49:17 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImNaYU9UcTBzSm5NYThST01sUGIxSWc9PSIsInZhbHVlIjoiMkdJTkFSRE9aUWFnc2tEaDJGeTRxbUIyaFNlVEVEb2dnUG5mRkJZZUF0eVBIckhuYVZmWlUzeVV1cExEbDJNclk5KzNkSmRxd1hHZmZHRHVPT2M3M0lGYjRLdm9ac2hwWkNOT2ZpVVRlZFZVUVM3VXMwYmdLYzhINWZaVlVURzUiLCJtYWMiOiI2YWUyNjExNTE4OWVlMzFhNTFkMjgzZWJiZTBjOWEwZThlOTczNGE5N2JhODE5MmRmMjA1ZDc4OTdkYmVkNjgzIiwidGFnIjoiIn0%3D; expires=Tue, 08 Apr 2025 02:49:17 GMT; Max-Age=7200; path=/; secureXSRF-TOKEN=eyJpdiI6ImNaYU9UcTBzSm5NYThST01sUGIxSWc9PSIsInZhbHVlIjoiMkdJTkFSRE9aUWFnc2tEaDJGeTRxbUIyaFNlVEVEb2dnUG5mRkJZZUF0eVBIckhuYVZmWlUzeVV1cExEbDJNclk5KzNkS" 1 => "laravel_session=eyJpdiI6InRCamRiOG9Hdk5lRC9rbnRiZy9tbHc9PSIsInZhbHVlIjoiTlNxOWVNaTZ1QnFhWlRvY2pmVncwN3dTdG5VRndrbHVtM081SlFhSmpFaWZZMnJkQmxFYVNoS3I5TEg1OU5FeEcxSHkzVVh4T2RidFJxbHA3dE5WVUZGNFZLSktaSUVPNHhCVis5Szk4bVR6SUdqNWNtSGJwY3BhTTMzWFdkZXciLCJtYWMiOiI4Yzg0MDcyOGU0YTI1ZTc1MzllOGQ3M2IzNTkxODZmNzg5NjNmNDRiNDc4MzJjOTkzNWQ3N2U0NzNkZTYyZmRkIiwidGFnIjoiIn0%3D; expires=Tue, 08 Apr 2025 02:49:17 GMT; Max-Age=7200; path=/; httponlylaravel_session=eyJpdiI6InRCamRiOG9Hdk5lRC9rbnRiZy9tbHc9PSIsInZhbHVlIjoiTlNxOWVNaTZ1QnFhWlRvY2pmVncwN3dTdG5VRndrbHVtM081SlFhSmpFaWZZMnJkQmxFYVNoS3I5TEg1OU5FeEcx" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImNaYU9UcTBzSm5NYThST01sUGIxSWc9PSIsInZhbHVlIjoiMkdJTkFSRE9aUWFnc2tEaDJGeTRxbUIyaFNlVEVEb2dnUG5mRkJZZUF0eVBIckhuYVZmWlUzeVV1cExEbDJNclk5KzNkSmRxd1hHZmZHRHVPT2M3M0lGYjRLdm9ac2hwWkNOT2ZpVVRlZFZVUVM3VXMwYmdLYzhINWZaVlVURzUiLCJtYWMiOiI2YWUyNjExNTE4OWVlMzFhNTFkMjgzZWJiZTBjOWEwZThlOTczNGE5N2JhODE5MmRmMjA1ZDc4OTdkYmVkNjgzIiwidGFnIjoiIn0%3D; expires=Tue, 08-Apr-2025 02:49:17 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6ImNaYU9UcTBzSm5NYThST01sUGIxSWc9PSIsInZhbHVlIjoiMkdJTkFSRE9aUWFnc2tEaDJGeTRxbUIyaFNlVEVEb2dnUG5mRkJZZUF0eVBIckhuYVZmWlUzeVV1cExEbDJNclk5KzNkS" 1 => "laravel_session=eyJpdiI6InRCamRiOG9Hdk5lRC9rbnRiZy9tbHc9PSIsInZhbHVlIjoiTlNxOWVNaTZ1QnFhWlRvY2pmVncwN3dTdG5VRndrbHVtM081SlFhSmpFaWZZMnJkQmxFYVNoS3I5TEg1OU5FeEcxSHkzVVh4T2RidFJxbHA3dE5WVUZGNFZLSktaSUVPNHhCVis5Szk4bVR6SUdqNWNtSGJwY3BhTTMzWFdkZXciLCJtYWMiOiI4Yzg0MDcyOGU0YTI1ZTc1MzllOGQ3M2IzNTkxODZmNzg5NjNmNDRiNDc4MzJjOTkzNWQ3N2U0NzNkZTYyZmRkIiwidGFnIjoiIn0%3D; expires=Tue, 08-Apr-2025 02:49:17 GMT; path=/; httponlylaravel_session=eyJpdiI6InRCamRiOG9Hdk5lRC9rbnRiZy9tbHc9PSIsInZhbHVlIjoiTlNxOWVNaTZ1QnFhWlRvY2pmVncwN3dTdG5VRndrbHVtM081SlFhSmpFaWZZMnJkQmxFYVNoS3I5TEg1OU5FeEcx" ] ]
        session_attributes
        0 of 0
        array:4 [ "locale" => "id" "_token" => "voqJApIAN4Fv7os2CCgc65qhRmMTZ4dR7lbIP2j8" "_previous" => array:1 [ "url" => "https://ai-care.atmatech.id/ibu-dan-anak/tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama" ] "_flash" => array:2 [ "old" => [] "new" => [] ] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-04-08 07:49:17GET/ibu-dan-anak/tiga-kelainan-kromosom-yang-menyebabkan-keguguran-di-trimester-pertama2113299