Brompheniramine

Brompheniramine
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Other Brands/Names

Alco Plus DMP, Alco Plus, Bromphenyl, Ares Kid Cold & Allergy.

 

How It Works

Brompheniramine is a medication from the antihistamine class. Histamine is a substance in the blood that increases the permeability of blood vessels, leading to fluid leakage from the blood vessels into the surrounding tissues. This results in swelling and the expansion of the blood vessels. Antihistamines like brompheniramine work by blocking histamine's action at H-1 receptors in cells, which helps reduce allergy symptoms and other related issues.

 

Indications

Brompheniramine is used to alleviate symptoms such as red, itchy, watery eyes; sneezing; and a runny nose caused by allergies, hay fever, or the flu. While it does not treat the root cause of these issues or speed up recovery, it is effective in providing relief from these bothersome symptoms.

 

Contraindications

  • Previous allergic reactions to brompheniramine.

  • Patients with conditions like breathing disorders (asthma, emphysema), diabetes, certain eye problems (e.g., glaucoma), heart conditions, high blood pressure, kidney or liver diseases, seizures, digestive problems (such as ulcers or blockages), hyperthyroidism, or urinary issues (such as difficulty urinating due to an enlarged prostate or urinary retention).

  • Use during the third trimester of pregnancy.

 

Side Effects

  • Possible side effects may include drowsiness, dizziness, headache, blurred vision, stomach discomfort, nausea, constipation, or dryness in the mouth, nose, or throat. If these effects continue or worsen, consult your doctor immediately.

  • A severe allergic reaction to brompheniramine is rare, but if you experience signs of a serious reaction, such as a skin rash, itching, swelling (especially of the face, tongue, or throat), intense dizziness, or difficulty breathing, seek emergency medical help.

 

Types

Brompheniramine is available in syrup form in 60 ml and 100 ml bottles.

 

Dosage

  • Adults: 4 mg every 4-6 hours.

  • Children:

    • 2-6 years: 1 mg every 4-6 hours.

    • 6-12 years: 2 mg every 4-6 hours.

    • 12 years and older: Same dosage as adults.

 

Safety

  • Brompheniramine may cause dizziness, drowsiness, or blurred vision. Avoid activities that require clear vision or alertness, such as driving or operating machinery, until you feel safe doing so.

  • Older adults may experience heightened sensitivity to side effects, including dizziness, drowsiness, and confusion, which may increase the risk of falls.

  • Children, particularly younger ones, may be more sensitive to antihistamines and could experience agitation.

  • This medication is passed into breast milk. Speak with your doctor before using it while breastfeeding.

 

Drug Interactions

Brompheniramine may increase the sedative effects of central nervous system depressants, such as barbiturates, anti-anxiety medications, sleep aids, opioid pain relievers, and antipsychotic drugs. It may also intensify the effects of other antimuscarinic medications (e.g., atropine, tricyclic antidepressants, monoamine oxidase inhibitors) and can mask the symptoms of ear damage caused by ototoxic drugs (e.g., aminoglycosides).

 

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Writer : dr David Wiliam
Editor :
  • dr Hanifa Rahma
Last Updated : Monday, 11 August 2025 | 22:56

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MedlinePlus. Brompheniramine. Medlineplus.gov.  Retrieved 10 February 2022, from https://medlineplus.gov/druginfo/meds/a682545.html