Kanker Pankreas dan Gejala yang Perlu Diwaspadai

Kanker Pankreas dan Gejala yang Perlu Diwaspadai
Ilustrasi nyeri perut sebagai salah satu gejala kanker pankreas. Credits: Freepik.

Bagikan :


Pankreas memiliki bentuk yang unik dengan panjang sekitar 25 cm. Pada perut, organ ini berada di bawah hati dan lambung serta di atas usus halus. Pankreas memiliki peran ganda, yaitu sebagai organ sistem pencernaan dan sistem hormonal. Pankreas bisa menghasilkan enzim yang membantu mencerna makanan dan hormon insulin yang membantu dalam regulasi gula darah.

Salah satu penyakit yang bisa muncul pada pankreas adalah kanker pankreas. Sayangnya, penyakit ini jarang ditemukan saat masih dalam stadium awal karena gejala umumnya baru muncul ketika penyakit berada dalam stadium lanjut.

 

Apa Itu Kanker Pankreas?

Kanker pankreas adalah jenis kanker yang terjadi ketika sel-sel pankreas tumbuh dan bermutasi secara tidak normal. Sebagian besar kanker pankreas bermula pada bagian duktus atau salurannya. Karena pada kebanyakan kasus kanker baru diketahui ketika sudah mencapai stadium lebih lanjut, hal ini membuat pengobatan kanker pankreas menjadi lebih sulit.

Kanker pankreas juga dikenal dengan resistansinya terhadap banyak jenis obat kanker yang umum. Akibatnya, kanker ini terkenal cukup sulit untuk diterapi.

Baca Juga: Pria Juga Bisa Terkena Kanker Payudara, Ini Gejalanya

Kanker pankreas dikategorikan menjadi dua jenis utama, di antaranya:

Kanker pankreas eksokrin

Kanker pankreas eksokrin adalah jenis kanker pankreas yang paling umum ditemukan, mencapai hampir 90% kasus kanker pankreas. Kanker ini bermula di sel-sel duktus pankreas.

Kanker pankreas neuroendokrin

Kanker pankreas neuroendokrin adalah jenis kanker pankreas yang lebih jarang terjadi, dengan perkiraan kurang dari 10% dari seluruh kasus kanker pankreas. Jenis kanker ini berkembang dari sel-sel pankreas yang berperan dalam menghasilkan hormon.

 

Gejala Kanker Pankreas

Gejala biasanya baru muncul ketika kanker sudah berada di stadium lebih lanjut, yaitu ketika jaringan tumor mulai memengaruhi organ lain di saluran cerna. Gejala yang bisa dirasakan pada kanker pankreas di antaranya:

  • Nyeri perut di bagian atas yang bisa menyebar hingga ke samping dan punggung
  • Kehilangan nafsu makan
  • Penurunan berat badan
  • Mual muntah
  • Jaundice, yaitu perubahan warna menjadi kuning pada kulit dan bagian putih mata
  • Tinja berwarna pucat seperti dempul 
  • Perubahan warna urine menjadi lebih gelap
  • Gatal-gatal
  • Munculnya diagnosis diabetes baru atau gejala diabetes menjadi sulit dikontrol
  • Rasa sakit dan bengkak di lengan atau kaki yang mungkin terjadi akibat pembekuan darah
  • Kelelahan
  • Kelemahan

Baca Juga: Ketahui Penyebab dan Faktor Risiko Kanker Ginjal

 

Pengobatan Kanker Pankreas

Skrining pada orang-orang tanpa gejala bisa dilakukan bila Anda memiliki risiko tinggi mengalami kanker pankreas. Bila ada riwayat kanker pankreas pada keluarga atau Anda memiliki gen yang dapat meningkatkan risiko Anda mengalami kanker, sebaiknya Anda berkonsultasi dengan dokter untuk mengetahui apakah bisa melakukan skrining kanker pankreas. Skriningnya sendiri mungkin meliputi pencitraan seperti MRI atau USG.

Orang dengan kanker pankreas memiliki tingkat kelangsungan hidup yang tidak sebaik jenis kanker lainnya. Untuk meningkatkan kelangsungan hidup, kanker perlu dideteksi dan diberi pengobatan sejak dini. 

Saat menyadari adanya gejala yang mencurigakan dan tidak kunjung hilang walaupun sudah melakukan pengobatan, Anda perlu memeriksakan diri ke dokter dan menjalani serangkaian pemeriksaan. Bila diduga kondisi Anda disebabkan oleh suatu keganasan, pemeriksaan bisa dilakukan untuk membantu mengetahui beberapa hal penting, di antaranya:

  • Di mana letak kanker berkembang
  • Sudah sampai mana tahap perkembangan sel kanker
  • Bagaimana kondisi kesehatan saat ini
  • Apakah sel-sel kanker telah menyebar ke organ lain selain pankreas

Setelah semua informasi dikumpulkan, dokter akan membahas pengobatan dan perawatan yang dibutuhkan, di antaranya:

  • Pembedahan bila memungkinkan dan jaringan tumor masih bisa diangkat
  • Bypass bilier apabila kanker menghalangi saluran empedu dan terjadi penumpukan empedu di kandung empedu
  • Bypass lambung apabila kanker menghalangi aliran makanan dari lambung
  • Terapi radiasi, kemoterapi atau kombinasi kedua terapi ini
  • Terapi obat bertarget
  • Terapi lainnya yang dibutuhkan sesuai kondisi

Karena gejala kanker pankreas mirip seperti gejala penyakit pada umumnya, segera periksakan diri bila gejala tersebut terus-menerus muncul. Anda juga bisa memanfaatkan layanan konsultasi kesehatan dengan mengunduh aplikasi Ai Care melalui App Store atau Play Store.

 

Mau tahu informasi seputar penyakit lainnya? Cek di sini, ya!

 

 

Writer : Agatha Writer
Editor :
  • dr Hanifa Rahma
Last Updated : Kamis, 30 November 2023 | 07:05

Mayo Clinic (2023). Pancreatic cancer. Available from: https://www.mayoclinic.org/diseases-conditions/pancreatic-cancer/symptoms-causes/syc-20355421 

Cleveland Clinic (2023). Pancreatic Cancer. Available from: https://my.clevelandclinic.org/health/diseases/15806-pancreatic-cancer 

Better Health. Pancreas. Available from: https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/pancreas 

National Cancer Institute (2023). Pancreatic Cancer Treatment (PDQ®)–Patient Version. Available from: https://www.cancer.gov/types/pancreatic/patient/pancreatic-treatment-pdq 

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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.88msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8273 and `categories`.`deleted_at` is null
      Bindings
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Backtrace
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Backtrace
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      Backtrace
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      Hints
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      Backtrace
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      Backtrace
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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