Serum Iron

Serum Iron
credits: medicalnewstoday.com

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Definisi

Pemeriksaan serum iron atau zat besi adalah pemeriksaan untuk mengukur kadar zat besi dalam serum darah. Serum darah adalah cairan yang tersisa bila sel darah merah dan faktor pembekuan darah dihilangkan. 

Zat besi sendiri adalah mineral esensial yang diperlukan tubuh dalam proses pembentukan sel darah merah. Tubuh memerlukan zat besi untuk menghasilkan sel darah merah yang sehat. Zat besi memiliki fungsi sebagai bahan penyusun hemoglobin, yaitu protein dalam sel darah yang membawa oksigen dari paru ke seluruh tubuh. Zat besi juga memiliki peran penting pada kesehatan otot, sumsum tulang, dan fungsi tubuh. 

 

Indikasi

Pemeriksaan serum iron merupakan salah satu parameter dalam pemeriksaan darah lengkap (complete blood count) yang rutin dilakukan. Pemeriksaan ini juga dilakukan dengan pemeriksaan lain seperti feritin atau Total Iron Binding Capacity (TIBC).

Pemeriksaan serum iron dilakukan untuk membantu diagnosis terkait anemia yang disebabkan kekurangan zat besi atau kondisi zat besi berlebih (seperti hemokromatosis) serta beberapa kondisi yang memerlukan pengawasan terkait kandungan zat besi dalam tubuh.

Selain itu, dokter akan meminta Anda melakukan pemeriksaan ini bila menunjukkan beberapa indikasi kadar zat besi dalam tubuh yang terlalu rendah atau terlalu tinggi, seperti:

  • Gejala kadar zat besi terlalu rendah
    • Kulit pucat
    • Kelelahan dan rasa lemas
    • Pusing, napas pendek, dan jantung berdebar
  • Gejala kadar zat besi terlalu tinggi
    • Nyeri sendi
    • Kekurangan energi
    • Sakit perut
    • Penurunan berat badan

Baca Juga: Penyakit Anemia Defisiensi Besi - Definisi, Penyebab, Gejala, dan Tata Laksana | AI Care (ai-care.id)

 

Kontraindikasi

Tidak ada kontraindikasi khusus terkait pemeriksaan serum iron.

 

Persiapan Sebelum Pemeriksaan

Pemeriksaan serum iron tidak membutuhkan persiapan khusus selain berpuasa. Anda akan diminta untuk berpuasa (tidak makan) beberapa jam sebelum pemeriksaan dilakukan.

Umumnya, pemeriksaan ini dilakukan di pagi hari. Informasikan pada dokter bila Anda mengonsumsi obat tertentu seperti antasida, suplemen zat besi dan NSAID, obat kolesterol, obat tekanan darah, obat gout, pil KB, dan estrogen serta makanan tinggi zat besi (seperti daging, sayur hijau, kacang-kacangan, susu) karena dapat memengaruhi hasil pemeriksaan.

 

Prosedur Pemeriksaan

Pemeriksaan serum iron sangat sederhana. Petugas laboratorium akan membersihkan lengan Anda dengan alkohol dan mengambil sedikit darah dari pembuluh darah vena di lengan menggunakan jarum suntik steril. Pada bayi, pengambilan darah dilakukan pada tumit. Selanjutnya, darah akan dimasukan ke dalam tabung darah dan diperiksa oleh petugas laboratorium di bawah mikroskop atau mesin khusus.

Risiko dalam proses pengambilan darah sangat kecil. Beberapa orang merasakan nyeri dan pusing saat pengambilan darah. Namun, hal ini biasanya hilang dengan cepat.

 

Nilai Normal dan Abnormal

Nilai normal pemeriksaan serum iron pada orang dewasa : 60 – 170 microgram per desiliter (mcg/dL)

  • 26 – 170 mcg/dL pada wanita
  • 76 – 198 mcg/dL pada pria

Nilai abnormal pada pemeriksaan serum iron bila kurang dari batas bawah normal atau lebih dari batas atas normal.

Baca Juga: Pemeriksaan Pemeriksaan TIBC - Indikasi, Prosedur, dan Hasil Pemeriksaan | AI Care (ai-care.id)

 

Hasil dan Saran (Pemeriksaan Lanjutan)

Rendah

Pada hasil pemeriksaan serum iron yang rendah dapat terkait pada beberapa kondisi. Pada wanita, terutama kondisi dalam siklus menstruasi turut menjadi salah satu penyebab hasil pemeriksaan serum yang rendah.

Beberapa faktor lain penyebab hasil pemeriksaan serum iron yang rendah di antaranya:

  • Adanya luka sehingga menyebabkan perdarahan saluran cerna, umumnya dapat disebabkan oleh konsumsi obat NSAID.
  • Adanya luka perdarahan di bagian lain dari tubuh.
  • Kondisi kehamilan.

Konsultasikan pada dokter Anda terkait hasil pemeriksaan serum iron yang rendah. Anda mungkin disarankan untuk mengonsumsi makanan kaya akan zat besi seperti hati sapi, daging merah, sayuran, biji – bijian dan suplemen zat besi.

Normal

Hasil pemeriksaan serum iron yang normal menunjukan keseimbangan dan kondisi sel darah merah yang berfungsi dengan optimal. Pertahankan kesehatan Anda dengan mengonsumsi gizi yang seimbang, aktivitas fisik yang cukup, serta pemeriksaan kesehatan yang rutin.

Tinggi

Pada hasil pemeriksaan serum iron yang tinggi menandakan tubuh memiliki kadar zat besi terlalu banyak. Selain itu, terdapat beberapa kondisi yang menyebabkan peningkatan kadar zat besi dalam tubuh, seperti :

  • Kondisi penyakit turunan yang langka seperti hemokromatosis.
  • Penyakit hati kronis, seperti sirosis hati, gagal hati, dan hepatitis.
  • Anemia hemolitik, di mana terjadi ketidaknormalan pemecahan sel darah merah.
  • Transfusi sel darah merah berlapis (multiple packed red blood cell).

Konsultasikan pada dokter Anda terkait hasil pemeriksaan serum iron yang tinggi. Pada kondisi serum iron yang tinggi disebabkan oleh penyakit hati kronis, hindari konsumsi makanan atau minuman yang dapat memperberat kerja hati, seperti alkohol. 

 

Konsultasikan ke Dokter yang Tepat

Bila hasil pemeriksaan serum iron Anda tidak normal, Anda dapat berkonsultasi dengan dokter umum untuk mendapatkan diagnosis dan terapi yang sesuai. Bila diperlukan, Anda juga dapat berkonsultasi dengan dokter spesialis penyakit dalam terkait kondisi Anda. Pada pasien anak-anak, dokter spesialis anak dapat memberikan informasi dan terapi yang lebih detil.

 

Mau tahu informasi seputar hasil pemeriksaan laboratorium, radiologi, dan lainnya? Cek di sini, ya!

Writer : dr Kevin Luke
Editor :
  • dr Ayu Munawaroh, MKK
Last Updated : Jumat, 29 September 2023 | 08:46

Iron and Total Iron Binding Capacity. (2022). Retrieved 17 August 2022, from https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=iron_total_iron_binding_capacity

Iron. (2021). Retrieved 17 August 2022, from https://www.testing.com/tests/iron/

Serum Iron Test. (2018). Retrieved 17 August 2022, from https://www.ucsfhealth.org/medical-tests/serum-iron-test

Serum Iron Test : High, Low, and Normal Ranges. (2018). Retrieved 17 August 2022, from https://www.medicalnewstoday.com/articles/322083

Serum Iron Test. (2022). Retrieved 17 August 2022, from https://www.mountsinai.org/health-library/tests/serum-iron-test

Iron Test. (2022). Retrieved 17 August 2022, from https://medlineplus.gov/lab-tests/iron-tests/

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    • ActivityLogger.php#174aicare_prod_new4.48msinsert into `activity_log` (`log_name`, `properties`, `batch_uuid`, `event`, `subject_id`, `subject_type`, `description`, `updated_at`, `created_at`) values ('default', '[]', null, 'updated', 4657, 'App\\Models\\Admin\\Post', 'updated', '2025-04-10 05:07:41', '2025-04-10 05:07:41')
      Bindings
      • 0: default
      • 1: []
      • 2: 
      • 3: updated
      • 4: 4657
      • 5: App\Models\Admin\Post
      • 6: updated
      • 7: 2025-04-10 05:07:41
      • 8: 2025-04-10 05:07:41
      Backtrace
      • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
      • vendor/spatie/laravel-activitylog/src/Traits/LogsActivity.php:88
      • app/Http/Controllers/WebController.php:779
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • single-post-healthpedia.blade.php#37aicare_prod_new1.22msselect * from `users` where `users`.`id` = 43 limit 1
      Bindings
      • 0: 43
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.single-post-healthpedia:37
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new7.29msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4163 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4163
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new12.21msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 1646 and `categories`.`deleted_at` is null
      Bindings
      • 0: 1646
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.29msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3859 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3859
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new6.52msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8160 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8160
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.05msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9965 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9965
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new9.26msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 1711 and `categories`.`deleted_at` is null
      Bindings
      • 0: 1711
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.98msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7741 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7741
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new8.42msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5843 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5843
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.23msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5257 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5257
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new5.8msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4658 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4658
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new5.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4659 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4659
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#122aicare_prod_new780μsselect * from `pages` where `slug` = 'about-us' limit 1
      Bindings
      • 0: about-us
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:122
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#547aicare_prod_new670μsselect * from `faqs` limit 1
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#551aicare_prod_new840μsselect * from `term_policies`
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
    153Post.php#?
    App\Models\Admin\Category
    21Category.php#?
    App\Models\Admin\Tag
    5Tag.php#?
    App\Models\TermPolicy
    3TermPolicy.php#?
    App\User
    2User.php#?
    App\Models\Admin\Page
    1Page.php#?
    App\Models\Admin\Faq
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