Definition
The bleeding time test (BT) is a clinical laboratory test used to measure the time it takes for the body to stop bleeding after an injury, or after a small intentional wound is made for testing purposes in a clinical setting.
Additionally, the bleeding time test helps assess the function of blood vessels and platelets (thrombocytes), particularly the ability of platelets to form blood clots. The test is performed by creating a small puncture wound on the skin to damage the capillary blood vessels beneath the surface. The time it takes for the body to stop bleeding is then measured.
The bleeding time test is often performed alongside other tests, such as coagulation time (CT), prothrombin time (PT), or activated partial thromboplastin time (APTT), as part of the blood hemostasis panel. This panel is used to assess how well blood clotting functions in the body.
Blood Clotting Process
Bleeding time is an important indicator of the blood clotting process (hemostasis), which involves a series of events to stop bleeding through blood clot formation. Platelets play a central role in this process, beginning with their attachment to the walls of injured blood vessels and continuing with the activation of blood clotting factors. If platelets are not functioning properly during any of these steps, the bleeding time will be prolonged. This can indicate an abnormality in the function of platelets or blood vessels.
Indication
A bleeding time test is typically requested by a doctor if you are experiencing symptoms that suggest a bleeding disorder, such as:
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Prolonged bleeding after an injury or trauma
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Easy bruising from minimal trauma or friction
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Excessive menstrual bleeding
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Frequent nosebleeds or bleeding gums that are difficult to stop
The bleeding time test is also used for screening in the following situations:
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To help establish a diagnosis of von Willebrand disease, a condition caused by abnormalities in certain blood clotting factors.
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For patients who are scheduled for surgical procedures or invasive procedures in outpatient clinics, to estimate the risk of excessive bleeding during these procedures. This is especially important for patients who:
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Have a bleeding disorder
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Are taking medications such as aspirin or non-steroidal anti-inflammatory drugs (NSAIDs)
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To assess platelet function disorders when platelet count and other blood clotting tests (such as PT or APTT) are within the normal range.
Contraindication
There are no known contraindications or conditions that would prevent someone from undergoing the bleeding time test.
Preparation Before the Test
No special preparation is required before the bleeding time test, and fasting is not necessary. However, it is important to consult with your doctor before undergoing the test. Certain medical conditions or medications may interfere with the test results, which could affect the accuracy of the findings. Medications like aspirin or NSAIDs can increase bleeding time, and you should inform your doctor if you are taking any of these drugs.
Test Procedure
The bleeding time test typically involves a minimal blood sample collected through a small injury to the capillary blood vessels. Laboratory personnel will wear special gloves and personal protective equipment (PPE) during the procedure.
The Duke method is commonly used for this test due to its simplicity. Before making the puncture, the technician will clean the area (usually the earlobe) with antiseptic gauze or 70% alcohol. A small needle is then inserted into the earlobe, creating a tiny puncture. As blood begins to flow from the wound, the technician starts a stopwatch. The technician will absorb the blood drops with filter paper every 30 seconds until the bleeding stops, indicated by no blood being absorbed into the paper. The stopwatch is then stopped, and the bleeding time is recorded.
The entire procedure takes only a few minutes, and the results can be determined shortly after the test is completed.
Normal and Abnormal Values
The normal range for bleeding time generally does not vary by age or gender. Using the Duke method, the following ranges are typically observed:
|
Value (Minutes) |
Interpretation |
|
1-3 |
Normal |
|
> 3 |
Prolonged |
However, different laboratories may use slightly different value ranges depending on the method employed and the guidelines they follow. For example, a bleeding time of 1 – 5 minutes might still be considered normal, while times longer than 5 minutes may be considered prolonged.
Results and Recommendations (Follow-up Tests)
Normal Results
If your bleeding time test results fall within the normal range, it generally indicates that you have no issues related to blood clotting, especially if you do not have symptoms like prolonged bleeding or easy bruising when exposed to minimal friction.
You are advised to maintain a healthy lifestyle to prevent conditions that could cause prolonged bleeding times. Regular health check-ups and good nutrition are essential for maintaining optimal health.
Prolonged Results
If the bleeding time test results show a prolonged value, it is important to consult a doctor for further evaluation. It is essential to consider that certain medications, such as aspirin or non-steroidal anti-inflammatory drugs (NSAIDs), can interfere with the results and cause prolonged bleeding time. Therefore, it is necessary to ensure that these medications have been ruled out before making conclusions about the results.
If the bleeding time is indeed prolonged, the doctor will likely recommend additional tests, such as a complete blood count (CBC) along with a peripheral blood smear, to examine the number and shape of platelets. Other tests might include platelet function tests or tests to assess the activity of other blood clotting factors.
Several factors can cause a prolonged bleeding time, including:
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Blood vessel disorders, such as collagen disorders found in Ehlers-Danlos syndrome
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Platelet (thrombocyte) function disorders, which may be accompanied by a decrease in platelet count (thrombocytopenia)
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The use of blood thinners or anticoagulants, which can interfere with platelet function
While a prolonged bleeding time can indicate a potential issue, it is important not to self-diagnose. You should consult with a healthcare professional for a comprehensive evaluation, especially if you experience symptoms or signs related to bleeding.
Consult the Right Doctor
For adults, it is recommended to consult a general practitioner for further testing or to begin treatment based on the diagnosis. If needed, you may be referred to an internist or a hematology-oncology specialist for further investigation into your bleeding time issues. For pediatric patients, abnormal results should be discussed with a pediatrician.
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- dr Hanifa Rahma
Medscape. Bleeding time. 2020 September. Available from: https://emedicine.medscape.com/article/2085022-overview#a1
Medline Plus. Bleeding time. 2022 April. Available from: https://medlineplus.gov/ency/article/003656.htm
National Library of Medicine. Bleeding time. 2021 August. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537233/