Diquafosol

Diquafosol
Credit: MIMS. Diquas adalah obat tetes mata yang digunakan untuk melumasi mata.

Bagikan :


Brand/Nama Lain

Nama dagang dari obat ini yang dapat ditemui di pasaran adalah Diquas.

 

Cara Kerja

Diquafosol termasuk obat pelumas mata. Obat ini bekerja dengan mengaktifkan reseptor P2Y yang terdapat pada lapisan selaput mata (konjungtiva) dan spesifiknya pada sel goblet. Sel ini berperan dalam memproduksi lendir dengan meningkatkan konsentrasi ion kalsium dalam cairan sel. Diquifosol akan menstimulasi produksi lendir dari sel goblet dan air mata dari sel epitel selaput mata, yang akan menghidrasi serta melumasi permukaan mata.

 

Indikasi

Obat ini digunakan untuk menghidrasi dan melumasi mata pada kondisi mata kering (dry eye).

 

Kontraindikasi

Obat diquafosol tidak dapat digunakan pada orang-orang yang menunjukkan reaksi alergi berat setelah menggunakan ini atau memiliki alergi pada komponen obatnya. Selain itu, terdapat beberapa hal yang perlu diperhatikan saat menggunakan diquafosol, yaitu:

  • Jaga agar mata tidak berkontak langsung dengan ujung botol tetes mata.
  • Jika menggunakan lebih dari 1 tetes obat, pemberian tetes selanjutnya dijeda selama minimal 5 menit.
  • Kelompok orang seperti ibu hamil, ibu menyusui dan anak-anak perlu memakai obat ini dengan hati-hati.

 

Efek Samping

Terdapat beberapa efek samping dari pemakaian obat yang perlu Anda perhatikan seperti di bawah ini:

  • Iritasi pada mata.
  • Keluarnya cairan atau lendir dari mata.
  • Selaput mata kemerahan.
  • Nyeri, gatal, atau rasa tidak nyaman pada mata.
  • Adanya sensasi seperti terdapat benda asing di mata.
  • Produksi air mata meningkat.
  • Infeksi pada bulu mata.
  • Silau saat melihat cahaya.
  • Pandangan kabur.
  • Lapisan kornea mata menipis.
  • Infeksi selaput mata (konjungtivitis).

 

Sediaan

Diquafosol tersedia dalam bentuk tetes mata dengan konsentrasi 3% dalam botol 5 mL.

 

Dosis

Orang dewasa bisa menggunakan diquafosol 3% dengan memberi 1 tetes obat pada mata yang mengalami keluhan sebanyak 6 kali dalam sehari.

 

Keamanan

Belum ada data yang cukup mengenai keamanan diquafosol pada kehamilan. Namun pada hewan percobaan tidak ada efek langsung atau tidak langsung yang berbahaya. Obat ini juga tidak diketahui dapat masuk ke dalam ASI atau tidak.

Selain itu, karena obat ini dapat menyebabkan pandangan kabur maka sebaiknya Anda tidak menyetir atau mengoperasikan suatu alat tertentu setelah memakai obat ini. Jika menggunakan lensa kontak sebaiknya dilepas terlebih dahulu dengan jarak 15 menit sebelum pemakaian.

 

Interaksi Obat

Belum ada data yang menunjukkan terkait interaksi obat ini dengan obat lain.

 

Mau tahu informasi seputar obat-obatan lainnya? Cek di sini, ya!

 

 

Writer : dr Luluk Ummaimah A
Editor :
  • dr Hanifa Rahma
Last Updated : Minggu, 16 April 2023 | 11:24

Diquafasol – Mims Indonesia. (2022). Retrieved 6 August 2022, from https://www.mims.com/indonesia/drug/info/diquafosol?mtype=generic

Diquas– Mims Indonesia. (2022). Retrieved 6 August 2022, from https://www.mims.com/indonesia/drug/info/diquas?type=brief&lang=id

Jun, I., Choi, S., Lee, GY. (2019). Effect of Preservative –free 3% Diquafasol in Patient with Pre-Existing Dry Eye Disease After Cataract Surgery: Randomized Clinical Trial. Scientifics Reports, 9(12659). doi: https://doi.org/10.1038/s41598-019-49159-0

Nam, K., Kim, HJ., Yoo, A. (2019). Efficacy and Safety of Topical 3% Diquafasol Ophtalmic Solution for The Treatment of Multifactorial Dry Eyes Disease: Meta Analysis of Randomized Clinical Trials. Opthalmic Res, 61(188-189) . doi: https://doi.org/10.1159/000492896

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      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#11aicare_prod_new980μsselect * from `categories` where `categories`.`id` = 4 and `categories`.`deleted_at` is null limit 1
      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.partials.article-popular:11
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new10.12msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9888 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9888
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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      Bindings
      • 0: 9858
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.46msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6418 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6418
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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      • 0: 1672
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
      • 0: 1667
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
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      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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    App\Models\Admin\Category
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    App\Models\TermPolicy
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