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Benefits of L-Arginine Supplements to Lower Blood Pressure

Benefits of L-Arginine Supplements to Lower Blood Pressure
Illustration of a blood pressure examination. Credit: Freepik

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L-arginine, also known as arginine, is an amino acid that the body can produce naturally. It is also found in foods such as nuts, fish, red meat, and supplements. L-arginine is recognized for its various health benefits, including its ability to lower blood pressure. What role does L-arginine play in reducing blood pressure? Continue reading for a detailed review.

 

What is L-Arginine?

L-arginine is an amino acid that serves as a building block for protein. It is essential for the production of nitric oxide, a molecule that plays a key role in various body functions, such as regulating blood flow and aiding cellular communication.

L-arginine is naturally produced from the breakdown of body proteins or obtained from protein-rich foods like red meat, poultry, milk, nuts, fish, and soy products.

Several studies suggest that L-arginine, when taken as a supplement, may offer a range of potential health benefits, including:

  • Increasing nitric oxide, which enhances blood flow and oxygen delivery to organs

  • Supporting the relaxation of cells that form blood vessels

  • Reducing inflammation and oxidative stress

  • Improving glucose metabolism and insulin sensitivity

  • Assisting in managing chronic conditions such as diabetes, obesity, hypertension, liver disease, and heart disease

  • Boosting athletic performance

  • Accelerating wound healing

Although L-arginine has several potential health benefits, further research is still needed to fully understand its effects and side effects when used as a supplement.

 

Is L-Arginine Effective in Lowering Blood Pressure?

L-arginine is a supplement often taken to help lower blood pressure. This amino acid helps relax blood vessels and widen arteries, resulting in a reduction in blood pressure. Research has shown that L-arginine can be beneficial in lowering blood pressure in individuals with pulmonary hypertension.

Other studies indicate that short-term use of L-arginine infusions may help lower blood pressure during pregnancy. Oral or infusion-based L-arginine use is considered safe during pregnancy if used short-term in the second and third trimesters.

However, this supplement is generally not necessary for most people and is most beneficial for those with amino acid deficiencies. L-arginine supplements may also interact with certain medications and worsen certain health conditions. Therefore, it is advisable to consult a doctor before using this supplement.

L-arginine may be more effective for heart health when combined with other vitamins, such as B-6 and B-12. However, additional research is required to determine the long-term benefits and potential side effects of this combination.

 

Side Effects of L-Arginine

In the short term, L-arginine supplements are generally considered safe for most individuals. However, L-arginine can cause side effects, particularly in the digestive tract, including bloating, abdominal pain, nausea, diarrhea, dizziness, and a drop in blood pressure.

L-arginine supplements should be avoided by:

  • Individuals with kidney disease or low blood pressure

  • Those who have recently had a heart attack

  • People preparing for surgery within the next two weeks

  • Individuals with allergies or asthma

 

While L-arginine can help lower blood pressure, it's important to consult your doctor before taking L-arginine supplements. Your doctor will assess whether the supplement is safe for you or recommend alternative options. You can also use the consultation feature on the Ai Care app, available for download on the App Store or Play Store.

 

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Writer : Ratih AI Care
Editor :
  • dr Hanifa Rahma
Last Updated : Monday, 21 April 2025 | 00:02

Mayo Clinic. L-Arginine: Does it Lower Blood Pressure?. Available from: https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/expert-answers/l-arginine/faq-20058052

Mayo Clinic. L-Arginine. Available from: https://www.mayoclinic.org/drugs-supplements-l-arginine/art-20364681

Kubala, J. (2025). Everything You Need to Know About L-arginine. Available from: https://www.healthline.com/nutrition/l-arginine#side-effects

WebMD. L-Arginine - Uses, Side Effects, and More. Available from: https://www.webmd.com/vitamins/ai/ingredientmono-875/l-arginine