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How It Works

Ciprofibrate is a medication used alongside a healthy diet to help lower "bad cholesterol" (Low-Density Lipoprotein or LDL) and triglycerides, while boosting "good cholesterol" (High-Density Lipoprotein or HDL). It works by increasing the activity of enzymes that break down fats in the blood. Ciprofibrate belongs to the class of drugs known as fibrates.

Indications

Ciprofibrate is primarily used to manage high cholesterol and triglyceride levels in individuals with hyperlipidemia (a condition where blood cholesterol levels are excessively high) who are at risk for cardiovascular diseases. It is effective in controlling the types of fats that can contribute to blockages in arteries, leading to cardiovascular diseases.

Contraindications

• Have a history of allergy to ciprofibrate.

• Have severe kidney or liver dysfunction.

• Are currently taking other fibrate medications.

Side Effects

• Ciprofibrate may cause several side effects, including gallstones and liver problems. If you experience any of the rare but serious side effects as follows, immediately notify your doctor:

  • Persistent nausea/vomiting

  • Loss of appetite

  • Stomach pain

  • Yellowing of the skin or eyes

  • Dark urine

• Additionally, ciprofibrate may cause muscle-related issues, which can lead to a serious condition known as rhabdomyolysis. Symptoms to watch for include:
  

  • Muscle pain or weakness (especially when accompanied by fever or unusual tiredness)

  • Signs of kidney problems, such as decreased urine output

• In some cases, other serious side effects may include:

  • Easy bruising or bleeding

  • Unusual tiredness

Types

Ciprofibrate is available in 100 mg caplets.

Dosage

Adults: The typical dosage is 100 mg daily.

Safety

• During pregnancy, ciprofibrate should only be used if absolutely necessary. Consult your doctor to discuss the risks and benefits before using it during pregnancy.

• It is unknown whether ciprofibrate is excreted in breast milk. Due to potential risks to the infant, breastfeeding is not recommended while taking this drug and for 5 days after stopping treatment. Always consult your doctor before breastfeeding.

Drug Interactions

Ciprofibrate, when taken alongside other fibrates, can increase the risk of rhabdomyolysis (a syndrome or collection of symptoms caused by damage and death of a skeleton muscle tissue. The breakdown of muscle tissue may result in acute kidney failure or even death) and myoglobinuria (conditions characterized by the presence of myoglobin in urine).

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