Other Brands/Names
Laxalosan, Laxadilac, Lacons, Lactulose, Duphalac, Constuloz, Constipen, Extralac, Dynalax, Starlax, Solac, Lantulos, Dulcolactol, Lactofid, Lactulax, Pralax, Graphalac, Opilax, Constipen.
How It Works
Indications
Used for medical conditions such as constipation or difficulty defecating (constipation), and decreased consciousness due to liver disease (hepatic encephalopathy).
Contraindications
Avoid using this drug if you have medical conditions such as galactosemia, intestinal obstruction (blockage of the intestinal tract), or intestinal perforation (a hole in the intestinal wall).
Side Effects
Nausea, vomiting, bloating, abdominal discomfort, stomach pain, diarrhea, and allergic reactions may occur.
Types
3.335 grams/5 mL - 45 mL, 60 mL, 100 mL, 120 mL, and 200 mL syrups.
Dosage
Purpose: To treat constipation
Adult dosage: 15-45 mL (3.335 grams/5 mL) as a single dose or split into two doses per day, with the dose adjusted based on response.
Children's dosage:
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Under 1 year: 5 mL (3.335 grams/5 mL) per day, given once daily or split into two doses.
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1–6 years: 5–10 mL per day, administered as a single dose or divided into two doses.
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7–14 years: 15 mL per day, taken as one dose or divided into two doses.
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Over 14 years: adult dosing, given once daily or divided into two doses.
Purpose: To treat hepatic encephalopathy
Adult dosage: 30-45 mL (3.335 grams/5 mL), 3-4 times daily.
Safety
Pregnancy:
This product is grouped as FDA Category B drug. Animal studies have not shown fetal harm, and there are no adequate, well-controlled studies in pregnant women, so use may be considered and is likely safe for pregnant women.
Drug Interactions
Thiazide blood pressure-lowering medications such as hydrochlorothiazide.
Concurrent use may increase the risk of potassium ion loss from the body.
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- dr Hanifa Rahma
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Mukherjee S, John S. Lactulose. [Updated 2021 Jul 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536930/
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