Cutaneous Larva Migrans

Cutaneous Larva Migrans

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Definisi

Cutaneous larva migrans (CLM) atau yang juga disebut dengan creeping eruption adalah penyakit kulit yang disebabkan oleh cacing tambang. Cacing termasuk ke dalam golongan kuman parasit. CLM biasanya ditemukan pada negara beriklim tropis. Penyakit infeksi kulit ini sering terjadi pada orang yang tinggal atau pernah bepergian ke negara tropis.

CLM menempati urutan kedua dari seluruh infeksi cacing di negara berkembang setelah infeksi cacing kremi. Jumlah keseluruhan kasusnya tinggi pada daerah beriklim hangat, dimana orang cenderung berjalan tanpa alas kaki seperti di pantai atau pada komunitas dengan sosio ekonomi yang rendah, serta berkontak dengan kotoran hewan.

 

Penyebab

CLM disebabkan oleh beberapa jenis larva cacing tambang yang berbeda. Larva adalah bentuk remaja dari cacing tambang. Cacing tambang yang paling sering menyebabkan CLM adalah spesies Ancylostoma. Ancylostoma braziliense yang merupakan cacing tambang pada anjing atau kucing peliharaan, adalah penyebab CLM tersering di Amerika dan Karibia. Selain itu, terdapat juga Ancylostoma caninum atau cacing tambang pada anjing, yang banyak ditemukan di Australia. Parasit hidup dan bertelur di dalam usus hewan peliharaan, seperti kucing dan anjing. Kotoran hewan yang ditinggali akan mengandung telur cacing. Telur kemudian menetas menjadi larva yang dapat menyebabkan infeksi. 

Infeksi terjadi ketika larva bersentuhan dengan kulit lalu masuk ke dalam tubuh. Larva banyak dijumpai di tanah atau pasir yang terkontaminasi. Untuk masuk ke dalam tubuh, larva menembus lapisan atas kulit. Orang yang berjalan tanpa alas kaki atau duduk di tanah tanpa penghalang seperti handuk, memiliki risiko yang lebih tinggi untuk terpapar larva cacing tambang. 

CLM paling sering dijumpai di daerah beriklim hangat dan lembap seperti Amerika Serikat bagian tenggara, Karibia, Amerika Tengah dan Selatan, Afrika, Timur Tengah, serta Asia Tenggara. CLM juga banyak ditemukan pada tempat dengan sanitasi yang buruk.

 

Faktor Risiko

Beberapa faktor risiko CLM antara lain:

1. Laki-Laki

Laki-laki tiga kali lebih berisiko mengalami CLM dibandingkan perempuan. Diperkirakan karena laki-laki lebih banyak menghabiskan waktu di luar ruangan, lebih banyak berkontak dengan tanah ketika bermain, dan lebih jarang diawasi oleh orang tua.

2. Usia 10-14 Tahun

Anak antara usia 10-14 tahun memiliki resiko 2 kali lebih besar dibandingkan anak kelompok usia yang lebih kecil. Hal ini disebabkan karena mereka lebih banyak beraktivitas di luar rumah, lebih banyak berkontak dengan tanah ketika bermain, dan sudah tidak diawasi ketat oleh orang tuanya.

3. Terpapar Pasir atau Tanah

Orang-orang yang berjalan tanpa alas kaki lebih mudah terpapar parasit cacing dibandingkan dengan yang memakai alas kaki, meskipun hanya sandal jepit sederhana. Kebiasaan tidak memakai alas kaki ini banyak dilakukan oleh anak-anak terutama saat bermain. Selain itu, pekerjaan yang banyak terpapar pasir atau tanah seperti ekskavasi atau konstruksi.

4. Lingkungan

Banyak faktor lingkungan yang dapat meningkatkan risiko terkena CLM, di antaranya:

    • Lingkungan luar
    • Kotoran hewan yang tidak dibersihkan
    • Jalanan yang tidak diaspal
    • Banyak hewan liar yang bermain dan buang air di jalan tanpa pengawasan
    • Kemiskinan atau pendapatan yang rendah
    • Hewan peliharaan belum diberikan obat cacing dan terkontaminasi tanah yang terinfeksi cacing

 

Gejala

Tanda-tanda CLM biasanya muncul pada hari pertama hingga kelima setelah infeksi, meski terkadang juga butuh waktu lebih lama. Tanda dan gejala yang umum meliputi:

  • Lesi atau tampilan tidak normal pada kulit berupa kemerahan dan berkelok-kelok yang terlihat pada kulit. CLM muncul sebagai lesi merah yang memiliki pola seperti ular. Hal ini disebabkan oleh pergerakan larva di bawah kulit. Lesi bisa bergerak hingga 2 cm dalam sehari
  • Rasa tidak nyaman, lesi CLM bisa terasa gatal, menyengat, atau menyakitkan
  • Pembengkakan pada area kulit yang terkena
  • CLM dapat terjadi di bagian tubuh mana saja, namun paling sering pada area yang kemungkinan sering terpapar tanah atau pasir yang terkontaminasi parasit, seperti kaki, bokong, paha, dan tangan

Karena lesi CLM bisa sangat gatal, orang dengan CLM cenderung menggaruk bagian tubuh yang terkena. Hal ini dapat merusak kulit dan meningkatkan risiko infeksi bakteri sekunder atau tambahan.

 

Diagnosis

Dokter dapat mendiagnosis CLM berdasarkan keluhan, riwayat aktivitas atau pekerjaan, serta melalui pemeriksaan lesi kulit yang khas. Jika Anda tinggal di daerah lembap atau tropis, informasi detail tentang lingkungan Anda sehari-hari dapat membantu dokter dalam menegakkan diagnosis.

 

Tata Laksana

CLM adalah penyakit yang bisa sembuh sendiri. Larva di bawah kulit biasanya mati dalam waktu 5 sampai 6 minggu tanpa pengobatan. Namun, pada beberapa kasus mungkin diperlukan waktu lebih lama untuk sembuh.

Penggunaan obat krim atau salep maupun obat minum dapat membantu infeksi sembuh lebih cepat. Dokter akan meresepkan obat antiparasit untuk membunuh cacing yang menginfeksi. Obat antiparasit yang beredar di Indonesia umumnya berupa obat minum. Selain meminum obat, dokter juga akan menyarankan untuk menjaga kebersihan kulit dengan mandi dua kali sehari menggunakan sabun.

 

Komplikasi

Komplikasi yang dapat terjadi akibat CLM antara lain:

  • Rasa gatal yang bisa mengganggu aktivitas
  • Infeksi bakteri sekunder, biasanya disebabkan oleh bakteri Staphylococcus aureus dan Streptococcus pyogenes, dapat menyebabkan selulitis atau infeksi meluas pada kulit dan jaringan di bawah kulit. Pada infeksi bakteri yang berkepanjangan, pernah dilaporkan adanya komplikasi radang ginjal pasca infeksi streptokokus
  • Reaksi alergi akibat cacing
  • Pada kasus yang langka, dilaporkan adanya sindrom Loeffler (sel darah putih eosinofil terkumpul di paru sebagai respon terhadap infeksi parasit)

 

Pencegahan

Jika Anda bepergian ke daerah endemik CLM, ada beberapa langkah yang dapat dilakukan untuk membantu mencegah infeksi:

  • Kenakan sepatu atau alas kaki untuk mengurangi risiko terpapar tanah atau pasir yang terkontaminasi larva cacing
  • Kenakan pakaian yang menutup paha dan bokong, area tubuh lainnya yang umum terkena infeksi CLM adalah paha dan bokong, yang dapat terpapar parasit saat sedang duduk atau berbaring
  • Hindari duduk atau berbaring pada tempat yang berpotensi terkontaminasi karena dapat meningkatkan risiko kulit terpapar larva
  • Gunakan handuk atau kain saat duduk atau berbaring di area yang mungkin terkontaminasi
  • Jika memungkinkan, hindari area yang sering dikunjungi banyak hewan, terutama anjing dan kucing. Jika Anda harus melakukan perjalanan melalui area tersebut, gunakanlah alas kaki
  • Pertimbangkan waktu dan musim saat akan bepergian, terutama perjalanan luar negeri. Beberapa daerah mengalami lonjakan infeksi CLM saat musim hujan
  • Beberapa negara berkembang menerapkan pengobatan pencegahan kepada orang-orang yang berisiko tinggi terkena infeksi, seperti:
    • Wanita hamil
    • Anak-anak
    • Memiliki pekerjaan yang banyak terpapar pasir, tanah, atau lebih berisiko terkena cacing tambang

 

Kapan Harus ke Dokter?

Jika Anda atau anak mengalami ruam kulit yang berbentuk khas dan disertai dengan keluhan infeksi CLM seperti yang disebutkan di atas, konsultasi dengan dokter sebelum infeksi meluas dan mengganggu aktivitas.

 

Mau tahu informasi seputar penyakit kulit dan rambut lainnya? Yuk, baca lebih banyak artikelnya di sini!

 

 

Writer : dr Aprilia Dwi Iriani
Editor :
  • dr Hanifa Rahma
Last Updated : Rabu, 17 April 2024 | 08:01

Schulman, JS. (2019). About cutaneous larva migrans. Retrieved 14 March 2022, from https://www.healthline.com/health/cutaneous-larva-migrans

Robles, DT. (2020). Cutaneous larva migrans. Retrieved 14 March 2022, from https://emedicine.medscape.com/article/1108784-overview

Maxfield, L., Crane, JS. (2021). Cutaneous Larva Migrans. Retrieved 14 March 2022, from https://www.ncbi.nlm.nih.gov/books/NBK507706/

Cristol, H. (2020). Hookworms. Retrieved 14 March 2022, from https://www.webmd.com/a-to-z-guides/hookworm-infection

Montgomery, S. (2019). Cutaneous larva migrans. Retrieved 14 March 2022, from https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectious-diseases/cutaneous-larva-migrans

Reichert, F., Pilger, D., Schuster, A., Lesshafft, H., Guedes de Oliveira, S., Ignatius, R., et al. (2018) Epidemiology and morbidity of hookworm-related cutaneous larva migrans (HrCLM): Results of a cohort study over a period of six months in a resource-poor community in Manaus, Brazil. PLoS Negl Trop Dis 12(7): e0006662. https://doi.org/ 10.1371/journal.pntd.0006662

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      • 0: penyakit-a-z
      • 1: obat-a-z
      • 2: pemeriksaan-a-z
      • 3: 0
      Hints
      • Use SELECT * only if you need all columns from table
      • The != operator is not standard. Use the <> operator to test for inequality instead.
      Backtrace
      • app/Repositories/Categories/CategoryHealtTopics.php:11
      • app/Http/Controllers/WebController.php:376
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • WebController.php#377aicare_prod_new123msselect * from `posts` where `status` = 1 and `publish_date` <= '2025-04-07 11:30:59' and `content_type` = 'article' and `posts`.`deleted_at` is null order by RAND() limit 7
      Bindings
      • 0: 1
      • 1: 2025-04-07 11:30:59
      • 2: article
      Hints
      • Use SELECT * only if you need all columns from table
      • ORDER BY RAND() is slow, try to avoid if you can. You can read this or this
      Backtrace
      • app/Http/Controllers/WebController.php:377
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • WebController.php#391aicare_prod_new9.35msupdate `posts` set `views_count` = 1177 where `id` = 3031
      Bindings
      • 0: 1177
      • 1: 3031
      Backtrace
      • app/Http/Controllers/WebController.php:391
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
    • ActivityLogger.php#174aicare_prod_new6msinsert into `activity_log` (`log_name`, `properties`, `batch_uuid`, `event`, `subject_id`, `subject_type`, `description`, `updated_at`, `created_at`) values ('default', '[]', null, 'updated', 3031, 'App\\Models\\Admin\\Post', 'updated', '2025-04-07 11:30:59', '2025-04-07 11:30:59')
      Bindings
      • 0: default
      • 1: []
      • 2: 
      • 3: updated
      • 4: 3031
      • 5: App\Models\Admin\Post
      • 6: updated
      • 7: 2025-04-07 11:30:59
      • 8: 2025-04-07 11:30:59
      Backtrace
      • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
      • vendor/spatie/laravel-activitylog/src/Traits/LogsActivity.php:88
      • app/Http/Controllers/WebController.php:391
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • single-post-healthpedia.blade.php#37aicare_prod_new900μsselect * from `users` where `users`.`id` = 27 limit 1
      Bindings
      • 0: 27
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.single-post-healthpedia:37
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new5.95msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7964 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7964
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new6.21msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 2743 and `categories`.`deleted_at` is null
      Bindings
      • 0: 2743
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new5.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6152 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6152
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new5.93msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 429 and `categories`.`deleted_at` is null
      Bindings
      • 0: 429
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#11aicare_prod_new810μsselect * from `categories` where `categories`.`id` = 6 and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: 6
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.partials.article-popular:11
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new5.95msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4369 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4369
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new6.03msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8036 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8036
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new6.42msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9018 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9018
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.28msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3733 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3733
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.11msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3579 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3579
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.24msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3720 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3720
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.39msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3164 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3164
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new6.95msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3485 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3485
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#122aicare_prod_new700μsselect * from `pages` where `slug` = 'about-us' limit 1
      Bindings
      • 0: about-us
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:122
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#547aicare_prod_new490μsselect * from `faqs` limit 1
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#551aicare_prod_new870μsselect * from `term_policies`
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
    103Post.php#?
    App\Models\Admin\Category
    25Category.php#?
    App\User
    4User.php#?
    App\Models\Admin\Tag
    4Tag.php#?
    App\Models\TermPolicy
    3TermPolicy.php#?
    App\Models\Admin\Page
    1Page.php#?
    App\Models\Admin\Faq
    1Faq.php#?
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        id
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        array:2 [ "old" => [] "new" => [] ]
        path_info
        /healthpedia-penyakit/cutaneous-larvae-migrans
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
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        []
        
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        request_cookies
        0 of 0
        array:2 [ "XSRF-TOKEN" => "EC8SHI3KIgNgyIowXMBpKgT92ZbEaHiakyINVcIy" "laravel_session" => "WpGBXTsqT0VK1EfPziUbdXd1tjGjiYFP8FwM7VOs" ]
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