Squalene

Squalene

Bagikan :


Brand/Nama Lain

Fishqua, Nutrimax Squalene 2000, Nature’s Health Squalene, Kawani Softgel Squalene, Vita Squalene, Extra Squalene Day/Night Cream, Squalene Transparant Bar Soap.

Cara Kerja

Squalene merupakan suatu senyawa yang biasanya diperoleh dari ekstraksi minyak hati ikan hiu. Squalene biasanya digunakan bersama dengan obat kanker untuk mengobati leukemia dan kanker lainnya, untuk mencegah penyakit radiasi dari terapi sinar-X kanker, untuk mencegah pilek, flu, serta untuk meningkatkan sistem kekebalan tubuh. Dalam bentuk sediaan topikal/obat luar, squalene dapat berfungsi sebagai pelembap, menjaga hidrasi kulit, serta bersifat sebagai antioksidan untuk menjaga kesehatan kulit.

Indikasi

Memelihara kesehatan tubuh dan meningkatkan sistem kekebalan tubuh.

Kontraindikasi

Riwayat alergi squalene sebelumnya.

Efek Samping

Squalene kemungkinan besar aman dikonsumsi orang dewasa bila digunakan jangka pendek. Efek samping kecil yang berhubungan dengan keluhan lambung dan usus telah dilaporkan. Dalam dosis tinggi, squalene dapat meningkatkan kadar kolesterol. Squalene dapat menyebabkan pneumonia pada orang yang secara tidak sengaja menghirupnya ke dalam paru-paru.

Sediaan

Squalene tersedia dalam bentuk kapsul lunak yang dikemas di dalam botol berisi 30/50/60/100 kapsul serta dalam bentuk topikal/obat luar untuk berbagai kondisi kulit (krim/serum/sabun cair/sabun padat).

Dosis

Untuk sediaan kapsul lunak: 1-2 kapsul sehari. Dosis yang tepat dari squalene tergantung pada beberapa faktor seperti usia pengguna, kesehatan, dan beberapa kondisi lainnya. Saat ini tidak ada informasi ilmiah yang cukup untuk menentukan kisaran dosis yang tepat untuk penggunaan squalene. Ingatlah bahwa produk alami belum tentu selalu aman. Pastikan untuk membaca dengan cermat dan mengikuti petunjuk yang tercantum pada label kemasan produk serta konsultasikan dengan dokter Anda atau tenaga profesional kesehatan lainnya sebelum menggunakan suplemen ini. Untuk sediaan obat luar, ikuti petunjuk yang tercantum dalam kemasan produk atau konsultasikan dengan dokter sebelum menggunakan produk squalene.

Keamanan

  • Kehamilan dan menyusui: Tidak cukup diketahui tentang keamanan penggunaan squalene selama kehamilan dan menyusui. Tetap utamakan keamanan dan hindari penggunaan suplemen ini selama masa kehamilan dan menyusui, atau konsultasikan dengan dokter kandungan Anda sebelum berencana mengonsumsi suplemen ini.
  • Orang yang memiliki kadar kolesterol tinggi: Orang dengan kolesterol tinggi harus menghindari mengonsumsi minyak hati ikan hiu atau menggunakannya hanya dalam jumlah yang terbatas. Minyak hati ikan hiu dapat meningkatkan kadar kolesterol bila digunakan dalam jumlah besar.

Interaksi Obat

Tidak ada interaksi yang terdokumentasi antara squalene dengan makanan atau obat-obatan. Namun, ini tidak berarti bahwa interaksi tidak dapat terjadi. Misalnya, squalene memiliki kandungan omega-3 yang tinggi, yang diketahui dapat menurunkan tekanan darah. Dengan demikian, mungkin dapat menyebabkan penurunan tekanan darah yang berlebihan (hipotensi) ketika dikonsumsi bersamaan dengan obat penurun tekanan darah. Demikian pula, mengingat efek pengencer darah dari omega-3 PUFA, diyakini bahwa konsumsi squalene dapat meningkatkan risiko pendarahan bila dikombinasikan dengan obat pengencer darah lainnya seperti aspirin dan warfarin. Namun demikian, bukti ilmiah masih belum mendukung asumsi-asumsi ini.

 

 

Writer : dr David Wiliam
Editor :
  • dr Nadia Opmalina
Last Updated : Jumat, 14 April 2023 | 19:59

BPOM RI. Squalene. cekbpom.pom.go.id. Retrieved 2 February 2022, from https://cekbpom.pom.go.id//home/produk/69bhknndt7v4km8sdutf8ashf5/all/row/10/page/3/order/4/DESC/search/1/squalene

MIMS Indonesia. Hi-Squa. Mims.com. Retrieved 2 February 2022, from https://www.mims.com/indonesia/drug/info/hi-squa

Web MD. Shark Liver Oil – Uses, Side Effects, and More. Webmd.com. Retrieved 2 February 2022, from https://www.webmd.com/vitamins/ai/ingredientmono-956/shark-liver-oil#

Healthline. Shark Liver Oil: Benefits, Uses, and Side Effects. Healthline.com. Retrieved 2 February 2022, from https://www.healthline.com/nutrition/shark-liver-oil

Zih R, Yin K, Jia Y. Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology. ncbi.nlm.nih.gov. Retrieved 2 February 2022, from  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253993/

Request history8.1.29PHP Version778msRequest Duration5MBMemory UsageGET healthpedia-{category}/{slug}Route
  • warninglog[14:02:21] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • warninglog[14:02:21] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • infolog[14:02:21] LOG.info: Attempting to authenticate with: { "username": "administrator", "url": ...
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      • app/Http/Controllers/WebController.php:259
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    • WebController.php#328aicare_prod_new13.18msselect * from `posts` where (`content_type` = 'healthpedia' and `slug` = 'squalene' or `slug_en` = 'squalene') and `status` = 1 and `publish_date` <= '2025-04-09 14:02:21' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
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      • app/Http/Controllers/WebController.php:328
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      • app/Http/Controllers/WebController.php:328
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    • WebController.php#332aicare_prod_new2.3msselect `healthpedia`.*, `healthpedia_post`.`post_id` as `pivot_post_id`, `healthpedia_post`.`healthpedia_id` as `pivot_healthpedia_id`, `healthpedia_post`.`created_at` as `pivot_created_at`, `healthpedia_post`.`updated_at` as `pivot_updated_at` from `healthpedia` inner join `healthpedia_post` on `healthpedia`.`id` = `healthpedia_post`.`healthpedia_id` where `healthpedia_post`.`post_id` = 2584 and `healthpedia`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:332
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      • app/Http/Controllers/WebController.php:369
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      • app/Http/Controllers/WebController.php:1386
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      • app/Http/Controllers/WebController.php:1386
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      • app/Http/Controllers/WebController.php:1386
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    • WebController.php#377aicare_prod_new132msselect * from `posts` where `status` = 1 and `publish_date` <= '2025-04-09 14:02:21' and `content_type` = 'article' and `posts`.`deleted_at` is null order by RAND() limit 7
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      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new4.63msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5225 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5225
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new4.83msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 1590 and `categories`.`deleted_at` is null
      Bindings
      • 0: 1590
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new4.57msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6444 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6444
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new7.56msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8033 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8033
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new7.95msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6480 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6480
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new8.2msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 9690 and `categories`.`deleted_at` is null
      Bindings
      • 0: 9690
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new11.92msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4524 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4524
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.9msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6989 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6989
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.64msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6842 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6842
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new7.58msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7021 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7021
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8aicare_prod_new8.06msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3097 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3097
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#122aicare_prod_new1.1msselect * from `pages` where `slug` = 'about-us' limit 1
      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:122
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#551aicare_prod_new1.04msselect * from `term_policies`
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
    45Post.php#?
    App\Models\Admin\Category
    21Category.php#?
    App\User
    3User.php#?
    App\Models\Admin\Tag
    3Tag.php#?
    App\Models\TermPolicy
    3TermPolicy.php#?
    App\Models\Admin\Healthpedia
    1Healthpedia.php#?
    App\Models\Admin\Page
    1Page.php#?
    App\Models\Admin\Faq
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        /healthpedia-obat/squalene
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        200
        
        status_text
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        format
        html
        content_type
        text/html; charset=UTF-8
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        ClearShow all
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