Famciclovir

Famciclovir
Famciclovir adalah antivirus yang digunakan sebagai pengobatan infeksi herpes.

Bagikan :


Brand/Nama Lain

Famvir

 

Cara Kerja

Famciclovir adalah antivirus yang digunakan untuk terapi infeksi herpes zoster dan herpes simpleks. Obat ini menghambat enzim yang berperan dalam pembentukan dan perbanyakan atau replikasi dari DNA virus herpes.

Bila Anda tertarik untuk membaca lebih jauh mengenai infeksi herpes simpleks, Anda bisa membacanya di sini: Herpes Simpleks - Definisi, Penyebab dan Faktor Risiko.

                 

Indikasi

Famciclovir digunakan sebagai pengobatan infeksi virus, seperti:

  • Herpes zoster atau cacar ular.
  • Herpes berulang di area bibir dan mulut.
  • Herpes kelamin baru atau yang sudah berulang.
  • Herpes di kulit dan membran mukosa berulang pada pasien HIV.

Bila Anda tertarik untuk membaca lebih jauh mengenai infeksi herpes zoster, Anda bisa membacanya di sini: Herpes Zoster - Definisi, Penyebab dan Faktor Risiko.

 

Kontraindikasi

Obat ini tidak boleh dikonsumsi bila Anda memiliki hipersensitivitas atau alergi terhadap antivirus famciclovir dan penciclovir. Sampaikan pada dokter jika Anda menderita penyakit ginjal.

 

Efek Samping

Penggunaan famciclovir dapat menyebabkan efek samping yang beragam, seperti berikut:

  • Pusing
  • Sakit kepala
  • Mual
  • Diare
  • Sembelit
  • Lemas
  • Demam
  • Kantuk
  • Kebas atau kesemutan
  • Nyeri perut
  • Sering buang angin
  • Gatal-gatal
  • Infeksi saluran napas atas
  • Nyeri punggung atau sendi

Segera cari bantuan medis bila timbul reaksi kulit hebat di seluruh tubuh atau alergi berat.

 

Sediaan

Famciclovir tersedia dalam bentuk tablet salut selaput 125 mg dan 250 mg.

 

Dosis

Herpes Zoster (Cacar Ular)

  • Dewasa: 500 mg tiga kali sehari selama 7 hari.
  • Pasien dengan penurunan kekebalan tubuh: 500 mg tiga kali sehari selama 10 hari.

 

Herpes Bibir Berulang

Dewasa: Tablet 1500 mg dikonsumsi dalam bentuk dosis tunggal.

 

Herpes Kelamin

  • Dewasa
    • Jika kondisi ini merupakan infeksi yang pertama kali diderita, tablet 250 mg diminum tiga kali sehari selama 5 hari.
    • Bila penyakit tergolong sebagai infeksi berulang, dosis 125 mg diminum dua kali sehari selama 5 hari.
  • Pasien dengan penurunan kekebalan tubuh
    • Tablet 500 mg dikonsumsi dua kali sehari selama 7 hari.

 

Keamanan

Obat ini tergolong sebagai kategori B pada kehamilan menurut FDA. Berdasarkan penelitian yang dilakukan pada hewan uji coba, obat tidak menunjukkan adanya efek samping pada janin. Famciclovir sejauh ini cukup aman diminum oleh ibu hamil.

Karena famciclovir dapat menyebabkan kantuk, jangan berkendara atau mengoperasikan alat berat selama pengobatan.

 

Interaksi Obat

Kadar obat famciclovir dapat meningkat dalam darah bila dikonsumsi bersama obat penurun kadar asam urat probenecid. Sementara itu, penyerapan obat ini tidak dipengaruhi oleh makanan, obat bisa diminum bersama makanan atau tanpa makanan.

 

Mau tahu informasi seputar obat-obatan lainnya? Cek di sini, ya!

 

 

Writer : dr Arifin Muhammad Siregar
Editor :
  • dr Hanifa Rahma
Last Updated : Jumat, 14 April 2023 | 04:35

Pusat Informasi Obat Nasional. (2022).Monografi- famsiklovir. Retrieved 15 September 2022, from https://pionas.pom.go.id/monografi/famsiklovir.

MIMS Indonesia. (2022). Famciclovir: Indication, Dosage, Side Effect, Precaution. Retrieved 15 September 2022, from https://www.mims.com/indonesia/drug/info/famciclovir?mtype=generic.

National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 3324, Famciclovir. Retrieved 15 September 2022 from https://pubchem.ncbi.nlm.nih.gov/compound/Famciclovir.

Request history8.1.29PHP Version849msRequest Duration7MBMemory UsageGET healthpedia-{category}/{slug}Route
  • infolog[23:00:09] LOG.info: Attempting to authenticate with: { "username": "administrator", "url": ...
  • errorlog[23:00:09] LOG.error: Error accessing doctor id: 63983202e088e5e18c0511d7 { "exception": "Undefi...
  • Booting (223ms)time
  • Application (626ms)time
  • 1 x Application (73.75%)
    626ms
    1 x Booting (26.25%)
    223ms
    11 templates were rendered
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    • 1x web.v2.partials.single.breadcrumbbreadcrumb.blade.php#?blade
    • 2x web.partials.single-sharesingle-share.blade.php#?blade
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    • 1x web.v2.partials.single.tagstags.blade.php#?blade
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    • 1x web.v2.partials.article-populararticle-popular.blade.php#?blade
    • 1x web.v2.partials.related-articlerelated-article.blade.php#?blade
    • 1x web.v2.partials.healthtopichealthtopic.blade.php#?blade
    • 1x layouts.v2.web_layoutweb_layout.blade.php#?blade
    uri
    GET healthpedia-{category}/{slug}
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    web
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    App\Http\Controllers
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    app/Http/Controllers/WebController.php:249-419
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    • WebController.php#259aicare_prod_new25.61msselect * from `posts` where (`content_type` = 'healthpedia' and `slug` = 'famciclovir' or `slug_en` = 'famciclovir') and `status` = 1 and `publish_date` <= '2025-04-09 23:00:09' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
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      • app/Http/Controllers/WebController.php:259
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      • app/Http/Controllers/WebController.php:259
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      • app/Http/Controllers/WebController.php:259
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    • WebController.php#328aicare_prod_new23.15msselect * from `posts` where (`content_type` = 'healthpedia' and `slug` = 'famciclovir' or `slug_en` = 'famciclovir') and `status` = 1 and `publish_date` <= '2025-04-09 23:00:09' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
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      • app/Http/Controllers/WebController.php:328
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    • WebController.php#328aicare_prod_new1msselect `users`.*, `post_editor`.`post_id` as `pivot_post_id`, `post_editor`.`user_id` as `pivot_user_id`, `post_editor`.`created_at` as `pivot_created_at`, `post_editor`.`updated_at` as `pivot_updated_at` from `users` inner join `post_editor` on `users`.`id` = `post_editor`.`user_id` where `post_editor`.`post_id` in (4988)
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      • app/Http/Controllers/WebController.php:328
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    • WebController.php#328aicare_prod_new610μsselect `users`.*, `post_english_editors`.`post_id` as `pivot_post_id`, `post_english_editors`.`user_id` as `pivot_user_id`, `post_english_editors`.`created_at` as `pivot_created_at`, `post_english_editors`.`updated_at` as `pivot_updated_at` from `users` inner join `post_english_editors` on `users`.`id` = `post_english_editors`.`user_id` where `post_english_editors`.`post_id` in (4988)
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      • app/Http/Controllers/WebController.php:328
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    • WebController.php#328aicare_prod_new5.83msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` in (4988) and `categories`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:328
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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    • WebController.php#332aicare_prod_new2.16msselect `healthpedia`.*, `healthpedia_post`.`post_id` as `pivot_post_id`, `healthpedia_post`.`healthpedia_id` as `pivot_healthpedia_id`, `healthpedia_post`.`created_at` as `pivot_created_at`, `healthpedia_post`.`updated_at` as `pivot_updated_at` from `healthpedia` inner join `healthpedia_post` on `healthpedia`.`id` = `healthpedia_post`.`healthpedia_id` where `healthpedia_post`.`post_id` = 4988 and `healthpedia`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:332
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      • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
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      • app/Http/Controllers/WebController.php:337
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    • WebController.php#369aicare_prod_new17.74msselect `tags`.*, `post_tag`.`post_id` as `pivot_post_id`, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`created_at` as `pivot_created_at`, `post_tag`.`updated_at` as `pivot_updated_at` from `tags` inner join `post_tag` on `tags`.`id` = `post_tag`.`tag_id` where `post_tag`.`post_id` = 4988
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      • app/Http/Controllers/WebController.php:369
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      • app/Http/Controllers/WebController.php:1386
      • app/Http/Controllers/WebController.php:372
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    • WebController.php#1386aicare_prod_new13.54msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 4276 and `posts`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:1386
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    • WebController.php#1386aicare_prod_new22.53msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 5638 and `posts`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:1386
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    • WebController.php#1386aicare_prod_new15.15msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 6437 and `posts`.`deleted_at` is null
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      • app/Http/Controllers/WebController.php:1386
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      • app/Repositories/Categories/CategoryHealtTopics.php:11
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    • WebController.php#377aicare_prod_new146msselect * from `posts` where `status` = 1 and `publish_date` <= '2025-04-09 23:00:09' and `content_type` = 'article' and `posts`.`deleted_at` is null order by RAND() limit 7
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      • app/Http/Controllers/WebController.php:377
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    • WebController.php#391aicare_prod_new9.67msupdate `posts` set `views_count` = 918 where `id` = 4988
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    • ActivityLogger.php#174aicare_prod_new9.36msinsert into `activity_log` (`log_name`, `properties`, `batch_uuid`, `event`, `subject_id`, `subject_type`, `description`, `updated_at`, `created_at`) values ('default', '[]', null, 'updated', 4988, 'App\\Models\\Admin\\Post', 'updated', '2025-04-09 23:00:09', '2025-04-09 23:00:09')
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      • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
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      • view::web.v2.partials.article-popular:8
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    • article-popular.blade.php#8aicare_prod_new5.26msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7277 and `categories`.`deleted_at` is null
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      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
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      Backtrace
      • view::web.v2.partials.article-popular:8
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      Backtrace
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Backtrace
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      Hints
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      Backtrace
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      Backtrace
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