Other Brands/Names

Alphadine, Alphadine gargle, Asepta, Betadine, Betadine Obat Kumur Antiseptik, Betadine Shampoo, Betadine vaginal preparations, Bioseption, Corsasep, Dinasept, Duvodine, Forinfec, Forinfec Gargle, Gamadine, Isodine gargle, Isodine skin, Molexdine, Molexdine obat kumur, Mugisept, Neo Iodine, Neo Iodine Larutan Topikal, Povikrom, Scansepta, Septadine, Septika Lar, Sterox, Vidisep

How It Works

Povidone iodine is an active ingredient of antiseptics used to prevent infection in wounds from falls, cuts, and surgical procedures. Its broad antibacterial activities arise from a complex formed with povidone that releases iodine to kill microbes.

Indications

This medicine is used to treat oral and throat infections, and it is also used for ongoing oral hygiene treatments. Povidone iodine is also applied as a topical antiseptic to reduce the risk of infection during certain medical procedures.

Contraindication

Povidone iodine is contraindicated in people with a history of thyroid disorders, including Hashimoto’s thyroiditis, endemic goiter, and nodular colloid goiter.

Side Effects

Side effects of povidoe iodine are uncommon. Possible adverse reactions include irritation of the oral mucosa, localized burning sensation, hives, blisters, itchiness, hypopigmented or white skin patches, skin peeling, redness, swelling, pain, or other signs of irritation.

Types

Here are a few povidone iodine preparations that are currently on the market:

• Solution

   

• Mouthwash

Dosage

Mouthwash

Adults and children ≥6 years: For a 1% povidone iodine mouthwash solution, gargle 10 mL for 30 seconds, four times daily for two weeks, or as directed by your physicians.

Topical Solution (liquid)

Adults and children ≥2 years old: Apply the povidone iodine solution to the affected skin area to help prevent infection.

Safety

Pregnancy:

Povidone iodine is categorized as FDA category D (there are evidences of potential risks to fetus based on human studies or post-marketing researches). However in life-threatening situations, potential benefits of using povidone iodine may outweigh the risks in pregnant patients.

Drug Interactions

Medicines containing lithium

Concurrent use of lithium with povidone iodine may increase the risks of thyroid-related reactions, which can lead to complications.

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