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Understanding the Causes and Triggers of Migraines

Understanding the Causes and Triggers of Migraines
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Migraines are intense headache episodes caused by disruptions in the brain's nerve activity. This condition typically presents as a throbbing headache, often affecting one side of the head. Many individuals also experience symptoms like nausea, vomiting, and heightened sensitivity to light and sound. Although the exact cause of migraines remains unclear, factors such as genetic predisposition and chemical imbalances in the brain are believed to contribute to the onset of these debilitating headaches.

 

Causes and Risk Factors of Migraine Headaches

While the precise cause of migraine headaches is still not fully understood, experts speculate that changes in the brainstem and their effect on the trigeminal nerve, responsible for transmitting pain signals, may play a key role in triggering migraines. According to the Mayo Clinic, disruptions in the balance of brain chemicals, such as serotonin, are also thought to be involved in the development of migraines. Low serotonin levels prompt the release of certain chemicals (neurotransmitters) that activate migraine pain.

Additionally, the release of prostaglandins, another group of chemicals, is believed to cause swelling of blood vessels around the nerves, contributing to the intense pain of a migraine. However, the exact mechanisms behind these chemical fluctuations in the brain remain elusive.

 

Triggers for Migraine

Although the underlying cause of migraines is not fully understood, various internal and external factors are known to act as triggers. WebMD lists several common migraine triggers:

1. Hormonal changes

Hormonal fluctuations, particularly in women, are a well-known trigger for migraines. Changes in estrogen levels, which occur before or during menstruation, pregnancy, and menopause, are commonly linked to migraine attacks. Additionally, the use of hormonal medications like birth control pills may also exacerbate migraines, although some women report fewer migraines when taking these medications.

2. Emotional stress

Stress, whether from anxiety, fear, or pressure, can also trigger migraines. When under stress, the brain releases compounds that can lead to severe headaches.

3. Dietary factors

Certain foods are known to trigger migraines. Processed foods, those high in salt, and artificial sweeteners such as aspartame and MSG are among the culprits. Skipping meals, especially breakfast, which can lead to a drop in blood sugar, is another common trigger for headaches.

4. Alcohol and caffeine consumption

Both alcohol and caffeine are known to trigger migraines. For individuals sensitive to these substances, limiting their intake may help reduce the frequency of headaches.

5. Weather changes

Shifts in weather, such as changes in air pressure, rain, or extreme heat, can provoke migraines. In areas with fluctuating weather patterns, it’s essential to take preventive measures, such as avoiding extreme temperatures and staying well-hydrated, to mitigate migraine risks.

6. Strenuous physical activities

Physical exertion, including exercise and sexual activity, can trigger migraines. If migraines are frequently experienced after these activities, reducing intensity may help prevent further headaches.

7. Changes in sleep patterns

Both insufficient sleep and oversleeping can contribute to migraines. Individuals experiencing sleep deprivation due to stress or jet lag are especially prone to these types of headaches.

 

In addition to the triggers mentioned above, several risk factors, such as age, genetics, and gender, play a role in determining the likelihood of developing migraines. Women, particularly those in their 30s with a family history of migraines, are more likely to experience frequent migraines compared to men. Most migraines subside on their own within a few days, but if the headache persists, it’s advisable to consult a doctor.

 

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Writer : Ratih AI Care
Editor :
  • dr Hanifa Rahma
Last Updated : Sunday, 10 August 2025 | 17:36

WebMD. (2020). Migraine Causes. Available from: https://www.webmd.com/migraines-headaches/migraines-causes#091e9c5e81459030-1-3 

Mayo Clinic. Overview. Available from: https://www.mayoclinic.org/diseases-conditions/migraine-headache/symptoms-causes/syc-20360201 

 

Upham, B. (2020). Causes and Risk Factors of MIgraine. Available from: https://www.everydayhealth.com/migraine/causes-risk-factors/