Ketahui Manfaat dan Efek Samping Obat Sertraline

Ketahui Manfaat dan Efek Samping Obat Sertraline
Ilustrasi obat sertraline. Credits: Freepik

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Sertraline adalah obat yang sering diresepkan oleh dokter untuk mengatasi berbagai gangguan mental, seperti depresi, gangguan kecemasan, dan gangguan obsesif kompulsif.

Obat ini termasuk dalam golongan selective serotonin reuptake inhibitor (SSRI), yang bekerja dengan cara meningkatkan kadar serotonin di otak. Seperti apakah manfaat dan efek samping dari penggunaan Sertraline? Simak ulasan berikut.

 

Manfaat Obat Sertraline

Sertraline merupakan obat antidepresan. Obat ini bekerja dengan cara menghambat penyerapan serotonin ke dalam sel saraf (neuron). Serotonin adalah zat kimia yang berperan penting dalam mengatur suasana hati, emosi, dan tidur. Dengan menghalangi penyerapan kembali serotonin ke neuron, maka suasana hati menjadi lebih stabil dan gejala depresi serta kecemasan bisa dikurangi.

Obat ini digunakan untuk mengobati berbagai kondisi kesehatan mental, di antaranya:

  • Depresi

Sertraline membantu meningkatkan suasana hati pada pasien dengan gangguan depresi mayor. Obat ini membantu memperbaiki suasana hati dengan meningkatkan kadar serotonin di otak, yang sering kali rendah pada orang dengan depresi.

Penelitian menunjukkan bahwa sertraline efektif dalam mengurangi gejala depresi seperti perasaan sedih, kehilangan minat pada aktivitas, dan kelelahan.

  • Gangguan panik

Sertraline membantu mengurangi frekuensi dan intensitas serangan panik.

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  • Gangguan obsesif-kompulsif

Sertraline membantu mengurangi gejala obsesif dan kompulsif pada orang dengan gangguan OCD.

  • Gangguan kecemasan sosial

Sertraline digunakan untuk mengurangi gejala kecemasan dalam situasi sosial. Obat ini bekerja dengan menyeimbangkan kadar serotonin, yang membantu menenangkan pikiran dan mengurangi perasaan cemas yang berlebihan.

  • Gangguan PTSD

Sertraline juga digunakan dalam pengobatan gangguan stres pasca-trauma (PTSD). Obat ini dapat membantu mengurangi gejala seperti kilas balik, mimpi buruk, dan kecemasan yang terkait dengan peristiwa traumatis yang dialami.

  • Gangguan dysphoric pramenstruasi (PMDD)

Sertraline digunakan untuk mengurangi gejala PMDD seperti perubahan suasana hati, mudah tersinggung, dan depresi.

 

Efek Samping Obat Sertraline

Meskipun memiliki banyak manfaat, sangat penting untuk memahami efek samping dari penggunaan obat ini.

Efek samping umum, di antaranya:

  • Mual
  • Diare
  • Mulut kering
  • Gangguan tidur
  • Sakit kepala
  • Berkeringat berlebihan
  • Penurunan nafsu makan

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Efek samping serius, di antaranya:

  • Perubahan suasana hati yang ekstrem
  • Meningkatnya kecemasan dan depresi
  • Pikiran untuk menyakiti diri
  • Reaksi alergi parah seperti ruam, pembengkakan, atau kesulitan bernapas

Penggunaan sertraline pada anak-anak dan remaja perlu diawasi dengan hati-hati karena dapat meningkatkan risiko perilaku atau pikiran untuk bunuh diri. Orang tua perlu selalu memantau anak-anak dan remaja yang mengonsumsi obat ini.

 

Orang yang Tidak Boleh Mengonsumsi Sertraline

Tidak semua orang dapat menggunakan sertraline untuk mengatasi masalah depresi dan kecemasan yang dialami. Beberapa kelompok perlu menghindari atau menggunakan obat ini dalam pengawasan ketat dokter. Kelompok tersebut di antaranya:

  • Orang dengan alergi terhadap sertraline atau bahan lain dalam obat ini
  • Pasien yang menggunakan obat Monoamine Oxidase Inhibitors atau dalam waktu 14 hari setelah penghentian MAOIs karena risiko interaksi obat yang serius
  • Orang dengan gangguan bipolar atau gangguan kejang
  • Ibu hamil dan menyusui

 

Sebelum memulai pengobatan dengan Sertraline, sangat penting untuk berkonsultasi dengan dokter. Jangan mengonsumsi obat ini tanpa resep dan pengawasan dokter untuk menghindari efek samping yang berbahaya.

Apabila Anda mengalami efek samping yang serius, maka sebaiknya konsultasikan kembali dengan dokter. Anda juga bisa memanfaatkan layanan konsultasi kesehatan Ai Care dengan mengunduhnya melalui App Store atau Play Store.

 

Mau tahu informasi seputar penyakit lainnya? Cek di sini, ya!

Writer : Agatha Writer
Editor :
  • dr Nadia Opmalina
Last Updated : Kamis, 3 Oktober 2024 | 05:13

Drugs.com (2024). Sertraline. Available from: https://www.drugs.com/sertraline.html 

Karen Berger, PharmD (2024). Sertraline (Zoloft) - Uses, Side Effects, and More. Available from: https://www.webmd.com/drugs/2/drug-1/sertraline-oral/details 

Better Health Channel. Depression - treatment and management. Available from: https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/depression-treatment-and-management 

Mayo Clinic (2019). Selective serotonin reuptake inhibitors (SSRIs). Available from: https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825 

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      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Backtrace
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
      • view::layouts.v2.web_layout:547
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
      • view::layouts.v2.web_layout:551
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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