Mengenal Penggunaan dan Efek Samping Omeprazole

Mengenal Penggunaan dan Efek Samping Omeprazole
Ilustrasi obat. Credit: Freepik

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Pengidap asam lambung umumnya tidak asing dengan obat omeprazole. Obat ini sering digunakan untuk mengatasi masalah asam lambung seperti mual, maag dan heartburn. Simak artikel berikut untuk mengetahui dosis, penggunaan dan efek samping penggunaan obat omeprazole.

 

Apa Itu Omeprazole?

Omeprazole adalah obat yang digunakan untuk mengatasi masalah perut dan esofagus tertentu seperti asam lambung dan ulkus. Obat ini membantu meredakan gejala masalah lambung dan tenggorokan seperti nyeri ulu hati, heartburn, dan kesulitan menelan.

Obat ini termasuk golongan proton pump inhibitors (PPIs) yang bekerja dengan menghambat produksi asam berlebih di lambung. Obat ini juga dapat digunakan untuk mencegah luka lambung, membantu menyembuhkan luka asam di lambung dan esofagus, dan membantu mencegah kanker esofagus.

Omeprazole bisa diberikan bagi Anda yang sering mengalami heartburn berulang yang terjadi selama 2 hari atau lebih dalam seminggu. Efek obat ini bisa Anda rasakan setelah dikonsumsi namun manfaat optimalnya bisa bertahan hingga 1-4 hari setelah dikonsumsi. 

Baca Juga: Kapan Harus Memeriksakan Diri ke Dokter bila Mual dan Muntah

 

Dosis dan Sediaan Omeprazole

Sediaan obat omeprazole mencakup:

  • Kapsul: 10 mg, 20 mg, 40 mg
  • Tablet salut selaput: 20 mg
  • Serbuk injeksi: 40 mg

 

Aturan Konsumsi Omeprazole

Dosis penggunaan omeprazole disesuaikan dengan tujuan pengobatan. Aturan penggunaan omeprazole di antaranya:

  • Tujuan pengobatan: Tukak lambung pada dewasa
    • Dosis pengobatan: 40 mg diminum 1 kali sehari
    • Durasi pengobatan: 4-8 minggu
  • Tujuan pengobatan: Tukak usus pada dewasa
    • Dosis pengobatan: 20 mg atau 40 mg diminum 1 kali sehari
    • Durasi pengobatan: 4-8 minggu
  • Tujuan pengobatan: GERD pada anak-anak di atas 1 tahun dan dewasa
    • Dosis pengobatan: 20 mg diminum 1 kali sehari
    • Durasi pengobatan: 4-8 minggu
  • Tujuan pengobatan: Infeksi H. pylori
    • Dosis pengobatan: 40 mg diminum 1 kali sehari dengan penggunaan 1 antibiotik
    • Durasi pengobatan: 1-2 minggu

Baca Juga: Begini Cara Atasi Mual dan Muntah Tanpa Obat-Obatan

 

Efek Samping Omeprazole

Seperti pengobatan pada umumnya, penggunaan omeprazole dapat menimbulkan efek samping ringan maupun serius. Efek samping pada anak-anak dapat berbeda dengan efek samping pada orang dewasa. 

Efek samping ringan pada orang dewasa yang dapat muncul antara lain:

  • Sakit kepala
  • Sakit perut
  • Mual
  • Diare
  • Muntah
  • Kembung

Efek samping pada anak-anak dapat mencakup hal-hal di atas, ditambah demam. Umumnya efek samping ringan akan mereda setelah beberapa minggu. Namun jika gejalanya semakin parah sebaiknya periksakan ke dokter. 

Efek samping yang serius

Beberapa efek samping serius yang bisa muncul antara lain:

  • Kadar magnesium rendah yang ditandai dengan kejang, detak jantung tidak teratur atau cepat, gemetar, gelisah, kelemahan otot, pusing, kejang pada tangan dan kaki, kram atau nyeri otot
  • Kekurangan vitamin B-12, ditandai dengan kesemutan, koordinasi otot yang buruk, perubahan menstruasi
  • Diare parah
  • Peradangan pada lapisan lambung yang ditandai dengan sakit perut, mual, muntah, penurunan berat badan
  • Kerusakan ginjal
  • Lupus eritematosus kulit 
  • Lupus eritematosus sistemik (SLE)
  • Polip kelenjar fundus (pertumbuhan pada lapisan perut yang biasanya tidak menimbulkan gejala)

Jika mengalami efek samping serius di atas maka sebaiknya segera periksakan ke dokter. 

 

Omeprazole merupakan obat yang banyak diresepkan pada pengidap masalah penyakit lambung. Penggunaan obat ini relatif aman, namun dapat menimbulkan efek samping serius. Saat mengonsumsi omeprazole, pastikan Anda telah berkonsultasi dengan dokter dan minum obat sesuai anjuran yang diberikan. 

Apabila Anda memiliki masalah kesehatan pencernaan sebaiknya periksakan ke dokter atau manfaatkan fitur konsultasi yang tersedia pada aplikasi Ai Care. 

 

Mau tahu tips dan trik kesehatan, pertolongan pertama, dan home remedies lainnya? Cek di sini, ya!

Writer : Ratih AI Care
Editor :
  • dr Nadia Opmalina
Last Updated : Selasa, 18 Juni 2024 | 05:45

Mayo Clinic. Omeprazole. Available from: https://www.mayoclinic.org/drugs-supplements/omeprazole-oral-route/description/drg-20066836#

Omeprazole. Available from: https://www.drugs.com/omeprazole.html

WebMD. Omeprazole. Available from: https://www.webmd.com/drugs/2/drug-3766-2250/omeprazole-oral/omeprazole-delayed-release-tablet-oral/details

Caporusciio, J. (2019). What to know about omeprazole. Available from: https://www.medicalnewstoday.com/articles/325840

University of Illiinois. (2021). Omeprazole, oral capsule/ Available from: https://www.medicalnewstoday.com/articles/omeprazole-oral-capsule

Medline Plus. Omeprazole. Available from: https://medlineplus.gov/druginfo/meds/a693050.html

NHS. Omeprazole. Available from: https://www.nhs.uk/medicines/omeprazole/about-omeprazole/

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      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8aicare_prod_new10.1msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3305 and `categories`.`deleted_at` is null
      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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      Hints
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      Backtrace
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      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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