Allylestrenol

Allylestrenol
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Other Brands/Names

Some brand names of allylestrenol available in Indonesia include Alena, Gravynon, Lestron, Nobor, Obstanon, Preabor, Preboran, Pregnabion, Pregnolin, Pregtenol, Premaston, Prestrenol, and Progeston.

 

How It Works

Allylestrenol is a medication commonly prescribed to help prevent miscarriage caused by low progesterone levels in the body. It works by imitating the natural hormone progesterone, triggering its hormonal effects to support progesterone production. This helps sustain pregnancy and reduces the risk of uterine contractions.

 

Indications

Medical conditions treated with allylestrenol include threatened miscarriage, recurrent miscarriage, and premature labor.

 

Contraindications

Contraindications to the use of allylestrenol include history of hypersensitivity or allergy to allylestrenol and liver disorders.

 

Side Effects

Side effects are uncommon, but in some cases may include blurred vision, double vision, migraine headaches, nausea, or vomiting.

 

Types

Allylestrenol is available as 5 mg tablets.

 

Dosage

Prevention of abortion or threatened miscarriage

Adults: 5 mg three times daily for 5–7 days. Treatment may be extended if needed, and the dose can be reduced gradually as miscarriage symptoms improve.

Prevention of recurrent abortion or miscarriage

Adults: 5–10 mg daily, starting as soon as pregnancy is confirmed. Treatment is continued for at least 1 month after the critical period.

Prevention of premature labor

Adults: The dose is adjusted individually based on medical advice, with a maximum of 40 mg daily.

 

Safety

Pregnancy:

FDA Category N (the potential risk to the fetus is not clearly established). Use should be done only under a doctor’s supervision.

 

Drug Interactions

There are no significant clinical reports to date regarding drug interactions of other drugs taken concurrently with allylestrenol. However, if you are taking other medications at the same time, it is recommended to consult a doctor to ensure safe use.

 

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Writer : dr Apri Haryono Hafid
Editor :
  • dr Ayu Munawaroh, MKK
Last Updated : Rabu, 27 Agustus 2025 | 12:39

Badan Pengawas Obat dan Makanan. Alliestrenol. Available from: https://pionas.pom.go.id/monografi/alliestrenol 

Drugbank. Allylestrenol. Available from: https://go.drugbank.com/drugs/DB01431

 

Mims Indonesia. Allylestrenol. Available from: https://www.mims.com/indonesia/drug/info/allylestrenol?mtype=generic