Other Brands/Names
Fishqua, Nutrimax Squalene 2000, Nature’s Health Squalene, Kawani Softgel Squalene, Vita Squalene, Extra Squalene Day/Night Cream, Squalene Transparant Bar Soap.
How It Works
Squalene is a compound typically sourced from shark liver oil. It is commonly taken alongside cancer treatments to help manage leukemia and other cancers, to reduce the risk of radiation sickness from therapeutic X-rays, to help prevent colds and flu, and to boost the immune system. As topical medications, squalene functions as a moisturizer, helps maintain skin hydration, and acts as an antioxidant to support skin health.
Indications
Helps in maintaining your general health and supports the immune system.
Contraindication
Prior history of allergy to squalene.
Side Effects
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Squalene is likely safe for adults when it is used for short term.
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Mild gastrointestinal issues have been reported.
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High doses of squalene may increase cholesterol serum levels.
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Accidental inhalation of squalene can lead to pneumonia.
Types
Squalene is available as softgel capsules in bottles of 30, 50, 60, or 100 capsules, and topical products for various skin concerns (cream, serum, liquid soap, or bar soap).
Dosage
Softgel capsules can be taken 1 to 2 capsules daily. The appropriate dose depends on factors such as age, health status, and other conditions. At present, there is not enough scientific information to define a suitable dosing range for squalene. Remember that natural products are not always safe. Read the product label carefully and consult your doctor or another healthcare professional before use. For topical products, follow the directions on the packaging or consult your doctor before using squalene preparations.
Safety
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Pregnancy and breastfeeding: Reseraches about the safety of squalene are insufficient. Prioritize caution when you take this medicine and avoid taking it during pregnancy and breastfeeding. Consult your obstetrician before considering taking this supplement.
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People with high cholesterol levels: Avoid shark liver oil or restrict its use. Large amounts may increase cholesterol levels.
Drug Interactions
There are no documented interactions between squalene and foods or medications; however, this does not mean interactions cannot occur. For example, squalene products can be high in omega-3 fatty acids, which are known to lower blood pressure, so taking them together with antihypertensive medicines may cause an excessive drop in blood pressure. Similarly, because omega-3 PUFAs have blood-thinning properties, squalene intake may increase bleeding risk when combined with other blood-thinning drugs such as aspirin or warfarin. Nevertheless, current scientific evidence does not yet confirm these assumptions.
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- dr Hanifa Rahma
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MIMS Indonesia. Hi-Squa. Mims.com. Retrieved 2 February 2022, from https://www.mims.com/indonesia/drug/info/hi-squa
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Healthline. Shark Liver Oil: Benefits, Uses, and Side Effects. Healthline.com. Retrieved 2 February 2022, from https://www.healthline.com/nutrition/shark-liver-oil
Zih R, Yin K, Jia Y. Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology. ncbi.nlm.nih.gov. Retrieved 2 February 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253993/