Bromelain

Bromelain

Kategori Obat

Umum Vitamin & Suplemen
Obat Bebas

Daftar Isi

Bagikan :


Brand/Nama Lain

Benozym, Elsazym, Enzycomb, Immuno Goodway, Noon Light, Natiflam, Herb Cal, Vegeblend, Fruit 18, Nutrimax Healthy Joint

Cara Kerja

Bromelain adalah sejenis enzim yang disebut enzim proteolitik. Bromelain ditemukan di dalam sari buah nanas dan di batang nanas. Bromelain membanntu tubuh memproduksi zat yang melawan nyeri atau rasa sakit dan pembengkakan/peradangan terutama di hidung, sinus-sinus, gusi, dan bagian tubuh lain setelah operasi atau cedera. Bromelain juga mengandung bahan kimia yang mungkin dapat melawan sel tumor dan memperlambat pembekuan darah.

Indikasi

Bromelain biasanya digunakan untuk kondisi seperti nyeri otot, nyeri, luka bakar, dan batu ginjal.

Kontraindikasi

  • Riwayat alergi terhadap nanas, lateks, bunga krisan, marigold, aster, gandum, seledri, wortel, serbuk sari cemara, serbuk sari rumput, atau tanaman lainnya.
  • Pembedahan: Bromelain dapat meningkatkan risiko perdarahan selama dan setelah operasi. Stop konsumsi bromelain setidaknya 2 minggu sebelum jadwal operasi.

Efek Samping

Bromelain biasanya jarang menimbulkan efek samping dan aman dikonsumsi bagi sebagian besar orang. Bromelain terbukti aman dengan dosis hingga 240 mg yang dikonsumsi hingga satu tahun. Bromelain mungkin dapat menimbulkan beberapa efek samping seperti diare dan nyeri perut.

Sediaan

Bromelain tersedia dalam bentuk tablet, kaplet, dan kapsul.

Dosis

Bromelain paling sering digunakan untuk orang dewasa dalam dosis 40-400 mg per oral setiap hari hingga 13 bulan. Konsultasikan dengan dokter Anda untuk mengetahui dosis apa yang terbaik untuk kondisi penyakit tertentu.

Keamanan

  • Kehamilan dan menyusui: Tidak ada informasi yang cukup untuk mengetahui apakah bromelain aman digunakan saat hamil atau menyusui. Tetap utamakan keamanan dan hindari penggunaan, atau konsultasikan dengan dokter Anda.
  • Konsultasikan dengan dokter Anda sebelum menggunakan bromelain jika Anda memiliki kondisi gangguan kesehatan, seperti gangguan perdarahan, asma, masalah jantung, penyakit hati atau ginjal, atau sakit maag.

Interaksi Obat

  • Mengonsumsi bromelain bersama dengan antibiotik dapat meningkatkan jumlah antibiotik yang diserap tubuh, sehingga konsumsi bromelain bersamaan dengan antibiotik seperti tetrasiklin dapat meningkatkan efek dan efek samping dari antibiotik ini.
  • Bromelain mungkin memperlambat pembekuan darah. Mengonsumsi bromelain bersama dengan obat-obatan yang juga memperlambat pembekuan darah dapat meningkatkan risiko terjadinya memar dan pendarahan.

Untuk informasi mengenai obat-obatan lainnya, silakan kunjungi laman ini ya!

Writer : dr David Wiliam
Editor :
  • dr Anita Larasati Priyono
Last Updated : Jumat, 22 Juli 2022 | 08:18
Tags : bromelain enzim proteolitik peradangan

National Center for Complementary and Integrative Health (NCCIH). Bromelain. 2020 May. https://www.nccih.nih.gov/health/bromelain

BPOM RI. Bromelain. cekbpom.pom.go.id. Retrieved 8 February 2022, from https://cekbpom.pom.go.id//home/produk/69bhknndt7v4km8sdutf8ashf5/all/row/10/page/3/order/4/DESC/search/5/bromelain

Web MD. Bromelain – Uses, Side Effects, and More. Webmd.com. Retrieved 8 February 2022, from https://www.webmd.com/vitamins/ai/ingredientmono-895/bromelain

Nourish by We MD. Bromelain (Bromelin). Webmd.com. Retrieved 8 February 2022, from https://www.webmd.com/diet/supplement-guide-bromelain-bromelin

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MessagesTimelineExceptionsViews11RouteQueries33Models109Livewire0MailsGateSessionRequest
Request history8.1.29PHP Version762msRequest Duration6MBMemory UsageGET healthpedia-{category}/{slug}Route
    • Booting (282ms)time
    • Application (479ms)time
    • 1 x Application (62.92%)
      479ms
      1 x Booting (37.08%)
      282ms
      11 templates were rendered
      • 1x web.v2.single-post-healthpediasingle-post-healthpedia.blade.php#?blade
      • 1x web.v2.partials.single.breadcrumbbreadcrumb.blade.php#?blade
      • 2x web.partials.single-sharesingle-share.blade.php#?blade
      • 1x web.v2.partials.single.editoreditor.blade.php#?blade
      • 1x web.v2.partials.single.tagstags.blade.php#?blade
      • 1x web.v2.partials.single.referensireferensi.blade.php#?blade
      • 1x web.v2.partials.article-populararticle-popular.blade.php#?blade
      • 1x web.v2.partials.related-articlerelated-article.blade.php#?blade
      • 1x web.v2.partials.healthtopichealthtopic.blade.php#?blade
      • 1x layouts.v2.web_layoutweb_layout.blade.php#?blade
      uri
      GET healthpedia-{category}/{slug}
      middleware
      web
      controller
      App\Http\Controllers\WebController@singleHealthpediaPost
      namespace
      App\Http\Controllers
      prefix
      where
      as
      web.single.healthpedia.post
      file
      app/Http/Controllers/WebController.php:249-419
      33 statements were executed (6 duplicates)Show only duplicates380ms
      • WebController.php#259aicare_prod_new19.24msselect * from `posts` where (`content_type` = 'healthpedia' and `slug` = 'bromelain' or `slug_en` = 'bromelain') and `status` = 1 and `publish_date` <= '2025-04-09 16:44:38' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
        Bindings
        • 0: healthpedia
        • 1: bromelain
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        • 3: 1
        • 4: 2025-04-09 16:44:38
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        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
        Backtrace
        • app/Http/Controllers/WebController.php:259
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#259aicare_prod_new1.36msselect `users`.*, `post_editor`.`post_id` as `pivot_post_id`, `post_editor`.`user_id` as `pivot_user_id`, `post_editor`.`created_at` as `pivot_created_at`, `post_editor`.`updated_at` as `pivot_updated_at` from `users` inner join `post_editor` on `users`.`id` = `post_editor`.`user_id` where `post_editor`.`post_id` in (2677)
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        Backtrace
        • app/Http/Controllers/WebController.php:259
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#259aicare_prod_new6.71msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` in (2677) and `categories`.`deleted_at` is null
        Hints
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        Backtrace
        • app/Http/Controllers/WebController.php:259
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#328aicare_prod_new12.69msselect * from `posts` where (`content_type` = 'healthpedia' and `slug` = 'bromelain' or `slug_en` = 'bromelain') and `status` = 1 and `publish_date` <= '2025-04-09 16:44:38' and `deleted_at` is null and `posts`.`deleted_at` is null limit 1
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        • 1: bromelain
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        • 4: 2025-04-09 16:44:38
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        • app/Http/Controllers/WebController.php:328
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#328aicare_prod_new1.15msselect `users`.*, `post_editor`.`post_id` as `pivot_post_id`, `post_editor`.`user_id` as `pivot_user_id`, `post_editor`.`created_at` as `pivot_created_at`, `post_editor`.`updated_at` as `pivot_updated_at` from `users` inner join `post_editor` on `users`.`id` = `post_editor`.`user_id` where `post_editor`.`post_id` in (2677)
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        • app/Http/Controllers/WebController.php:328
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#328aicare_prod_new1.12msselect `users`.*, `post_english_editors`.`post_id` as `pivot_post_id`, `post_english_editors`.`user_id` as `pivot_user_id`, `post_english_editors`.`created_at` as `pivot_created_at`, `post_english_editors`.`updated_at` as `pivot_updated_at` from `users` inner join `post_english_editors` on `users`.`id` = `post_english_editors`.`user_id` where `post_english_editors`.`post_id` in (2677)
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        • app/Http/Controllers/WebController.php:328
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#328aicare_prod_new6.16msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` in (2677) and `categories`.`deleted_at` is null
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        • app/Http/Controllers/WebController.php:328
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#332aicare_prod_new1.82msselect `healthpedia`.*, `healthpedia_post`.`post_id` as `pivot_post_id`, `healthpedia_post`.`healthpedia_id` as `pivot_healthpedia_id`, `healthpedia_post`.`created_at` as `pivot_created_at`, `healthpedia_post`.`updated_at` as `pivot_updated_at` from `healthpedia` inner join `healthpedia_post` on `healthpedia`.`id` = `healthpedia_post`.`healthpedia_id` where `healthpedia_post`.`post_id` = 2677 and `healthpedia`.`deleted_at` is null
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        • app/Http/Controllers/WebController.php:332
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#337aicare_prod_new930μsselect * from `categories` where `categories`.`id` = 8 and `categories`.`deleted_at` is null limit 1
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        • app/Http/Controllers/WebController.php:337
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#369aicare_prod_new16.42msselect `tags`.*, `post_tag`.`post_id` as `pivot_post_id`, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`created_at` as `pivot_created_at`, `post_tag`.`updated_at` as `pivot_updated_at` from `tags` inner join `post_tag` on `tags`.`id` = `post_tag`.`tag_id` where `post_tag`.`post_id` = 2677
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        • 0: 2677
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        • app/Http/Controllers/WebController.php:369
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#1386aicare_prod_new13.08msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 5209 and `posts`.`deleted_at` is null
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        • app/Http/Controllers/WebController.php:1386
        • app/Http/Controllers/WebController.php:372
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • WebController.php#1386aicare_prod_new11.75msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 5210 and `posts`.`deleted_at` is null
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        • app/Http/Controllers/WebController.php:1386
        • app/Http/Controllers/WebController.php:372
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • WebController.php#1386aicare_prod_new16.47msselect `posts`.*, `post_tag`.`tag_id` as `pivot_tag_id`, `post_tag`.`post_id` as `pivot_post_id` from `posts` inner join `post_tag` on `posts`.`id` = `post_tag`.`post_id` where `post_tag`.`tag_id` = 885 and `posts`.`deleted_at` is null
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        Backtrace
        • app/Http/Controllers/WebController.php:1386
        • app/Http/Controllers/WebController.php:372
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • CategoryHealtTopics.php#11aicare_prod_new1.31msselect * from `categories` where (`slug` != 'penyakit-a-z' and `slug` != 'obat-a-z' and `slug` != 'pemeriksaan-a-z' and `parent_id` = '0') and `categories`.`deleted_at` is null order by `order` asc
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        • 1: obat-a-z
        • 2: pemeriksaan-a-z
        • 3: 0
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        Backtrace
        • app/Repositories/Categories/CategoryHealtTopics.php:11
        • app/Http/Controllers/WebController.php:376
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • WebController.php#377aicare_prod_new145msselect * from `posts` where `status` = 1 and `publish_date` <= '2025-04-09 16:44:38' and `content_type` = 'article' and `posts`.`deleted_at` is null order by RAND() limit 7
        Bindings
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        • 1: 2025-04-09 16:44:38
        • 2: article
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        • ORDER BY RAND() is slow, try to avoid if you can. You can read this or this
        Backtrace
        • app/Http/Controllers/WebController.php:377
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • WebController.php#391aicare_prod_new7.65msupdate `posts` set `views_count` = 495 where `id` = 2677
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        Backtrace
        • app/Http/Controllers/WebController.php:391
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • ActivityLogger.php#174aicare_prod_new5.92msinsert into `activity_log` (`log_name`, `properties`, `batch_uuid`, `event`, `subject_id`, `subject_type`, `description`, `updated_at`, `created_at`) values ('default', '[]', null, 'updated', 2677, 'App\\Models\\Admin\\Post', 'updated', '2025-04-09 16:44:38', '2025-04-09 16:44:38')
        Bindings
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        • 1: []
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        • 4: 2677
        • 5: App\Models\Admin\Post
        • 6: updated
        • 7: 2025-04-09 16:44:38
        • 8: 2025-04-09 16:44:38
        Backtrace
        • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
        • vendor/spatie/laravel-activitylog/src/Traits/LogsActivity.php:88
        • app/Http/Controllers/WebController.php:391
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • single-post-healthpedia.blade.php#37aicare_prod_new1.17msselect * from `users` where `users`.`id` = 34 limit 1
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        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
        Backtrace
        • view::web.v2.single-post-healthpedia:37
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • article-popular.blade.php#8aicare_prod_new11.52msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6765 and `categories`.`deleted_at` is null
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        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • article-popular.blade.php#8aicare_prod_new10.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4953 and `categories`.`deleted_at` is null
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        Backtrace
        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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        Hints
        • Use SELECT * only if you need all columns from table
        Backtrace
        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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        Hints
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        Backtrace
        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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        Backtrace
        • view::web.v2.partials.article-popular:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
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        Backtrace
        • view::web.v2.partials.related-article:8
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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        Backtrace
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        Backtrace
        • view::web.v2.partials.related-article:8
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        Backtrace
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        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
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