Pipemidic Acid

Pipemidic Acid
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Other Brands/Names

Impresial, Urinter, Uriseptic, Urixin, Uromix, Urotractin, Utrex.

 

How It Works

Pipemidic acid is a quinolone antibiotic that works by inhibiting the growth of bacteria responsible for infections. It is specifically used to treat urinary tract infections (UTIs).

 

Indications

Pipemidic acid is used to treat urinary tract infections caused by both gram-negative and gram-positive bacteria. A UTI is an infection that affects one or more organs in the urinary tract, which includes the kidneys, ureters (the tubes that connect the kidneys and bladder), bladder, and urethra (the tube that carries urine).

 

Contraindications

This medication should not be used by individuals who:

  • Have a history of allergy to pipemidic acid or other quinolone antibiotics

  • Have severe kidney disorders

 

Side Effects

Common side effects of pipemidic acid include:

  • Nausea

  • Vomiting

  • Abdominal pain

  • Dizziness or vertigo

Although serious allergic reactions are rare, they still can occur in some individuals. Seek medical attention immediately if you experience:

  • Skin rash

  • Itching or swelling, especially of the face, tongue, or throat

  • Severe dizziness

  • Difficulty breathing

 

Types

Pipemidic acid is available in the forms of 400 mg caplets, tablets, and capsules.

 

Dosage

Pipemidic acid is typically taken twice daily, every 12 hours. The treatment should be continued for at least 10 days to prevent re-infection.

 

Safety

There are no studies available on the safety and effects of this medication on pregnant women and fetuses. It is also unknown whether pipemidic acid is excreted in breast milk. Discuss the risks and benefits with your doctor if you are pregnant or planning to breastfeed.

 

Drug Interactions

Increased drug effects

If pipemidic acid is taken alongside acarbose (a medication used in diabetes treatment), it may increase the effects of acarbose.

 

Decreased drug levels

Taking pipemidic acid with acetaminophen (used for pain and fever relief) may reduce the absorption of acetaminophen. This can cause a decrease of its effectiveness.

 

Worsening heart rhythm disorders

Combining pipemidic acid with adenosine may increase the risk or severity of QT interval prolongation, a heart disorder that can cause irregular heartbeats, fainting, or even sudden death.

 

Looking for more information about other drugs? Click here!

 

 

Writer : dr David Wiliam
Editor :
  • dr Hanifa Rahma
Last Updated : Wednesday, 20 August 2025 | 13:59

BPOM RI. Pipemidic Acid. cekbpom.pom.go.id. Retrieved 13 March 2022, from https://cekbpom.pom.go.id//home/produk/69bhknndt7v4km8sdutf8ashf5/all/row/10/page/1/order/4/DESC/search/5/pipemidic%20acid 

Pusat Informasi Obat Nasional BPOM. Asam Pipemidat). Pionas.pom.go.id. Retrieved 13 March 2022, from https://pionas.pom.go.id/monografi/asam-pipemidat 

MIMS Indonesia. Urixin. Mims.com. Retrieved 13 March 2022, from https://www.mims.com/indonesia/drug/info/urixin?type=brief&lang=id 

MIMS Indonesia. Urotractin. Mims.com. Retrieved 13 March 2022, from https://www.mims.com/indonesia/drug/info/urotractin 

 

Pipemidic Acid. Go.drugbank.com.  Retrieved 13 March 2022, from https://go.drugbank.com/drugs/DB13823