Other Brand/Names

Erleada.

How It Works

Apalutamide is a medication frequently used to manage prostate cancer that has metastasize to other parts of the body or is at high risk of spreading, even if it has not yet. It is also effective for cases still responding to treatment aimed at lowering testosterone levels. Apalutamide functions by preventing the growth and reproduction of prostate cancer cells, which helps to shrink tumors.

Indications

It is prescribed for prostate cancer, both with and without metastasis.

Contraindications

Apalutamide should not be used by individuals with a known hypersensitivity or allergy to the drug, those who are pregnant, trying to conceive, or currently breastfeeding.

Side Effects

While side effects are uncommon, some individuals may experience the following:

• Fatigue

• Joint pain

• Red spots on the skin

• Weight loss

• Decreased appetite

• Itching

• Diarrhea

• Muscle pain

• Frequent falls

• Hot flashes

Types

Apalutamide is available in the following form:

• 60 mg Tablets

Dosage

• Dosage for adults: 240 mg taken once a day.

Safety

Pregnancy:

FDA Category N (the potential risk to the fetus has not been fully established), so it is important to consult with a doctor before use to ensure appropriate monitoring.

Drug Interactions

Ketoconazole

Using apalutamide with ketoconazole can lead to higher levels of apalutamide in the bloodstream, increasing the risk of side effects. Medical supervision is required when using these medications together.

Haloperidol

Combining apalutamide with haloperidol have the potential to cause a dangerous issue, which is an elevated risk of heart rhythm issues. This combination can be hazardous, so it is essential to use them under direct medical supervision.

Digoxin

When apalutamide is taken alongside digoxin, there is a risk of reduced digoxin levels in the blood, which can lessen its effectiveness. Medical supervision is required when these drugs are used together.

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